anti-Mesoderm Posterior 2 Homolog (Mouse) (Mesp2) 抗体

Mesp2 encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. 再加上,我们可以发Mesp2 蛋白 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
Mesp2 17293 O08574
Mesp2 293046  
Mesp2 145873 Q0VG99
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Showing 10 out of 35 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 WB <b>WB Suggested Anti-MESP2 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>SP2/0 cell lysate 100 μL Log in to see 2至3个工作日
$229.00
详细
非结合性 WB Western blot analysis of MESP2 expression in A549 (A), NS-1 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
小鼠 非结合性 ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using MESP2 mAb against human MESP2 recombinant protein. (Expected MW is 31.4 kDa) 100 μg Log in to see 2至3个工作日
$430.10
详细
小鼠 非结合性 ELISA, WB 100 μg Log in to see 7至9个工作日
$551.83
详细
小鼠 非结合性 WB 100 μg Log in to see 7至9个工作日
$493.17
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小鼠 非结合性 ELISA, WB 100 μg Log in to see 2至3个工作日
$343.75
详细
小鼠 非结合性 IF, ELISA Immunofluorescence of monoclonal antibody to MESP2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11至12个工作日
$430.00
详细
小鼠 非结合性 WB Western Blot: MESP2 Antibody [NBP1-80219] - SP2/0 cell lysate, concentration 1.25ug/ml. 100 μL Log in to see 8至11个工作日
$408.19
详细
非结合性 WB   100 μL Log in to see 7至9个工作日
$375.83
详细
小鼠 Alexa Fluor 405 ELISA, WB   0.1 mL Log in to see 8至11个工作日
$538.13
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通过反应活性、应用领域、克隆类型和共轭标记 Mesp2 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine)


Rat (Rattus)


Human ,
,
,
, , , , , , , , , , , , ,

引用最多的anti-Mesp2 抗体

  1. Human Monoclonal Mesp2 Primary Antibody for ELISA, WB - ABIN1098148 : Qiu, Zhou, Jiang, Ji, Ding, Lv, Liu, Tang, Cheng, Qiu: Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis. in Studies in health technology and informatics 2012 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Polyclonal Mesp2 Primary Antibody for WB - ABIN2779870 : Morimoto, Takahashi, Endo, Saga: The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. in Nature 2005 (PubMed)
    Show all 2 Pubmed References

更多抗Mesp2的相互作用对抗体

Mouse (Murine) Mesoderm Posterior 2 Homolog (Mouse) (Mesp2) interaction partners

  1. Studies indicate that mesodermal posterior 1 (Mesp1 (显示 MESP1 抗体)) and mesodermal posterior 2 (Mesp2) double-knockout embryos exhibited defective development of the embryonic mesoderm.

  2. conclusion was supported by analyses of Mesp2 KO and Ripply1/2 double KO embryos lacking rostral and caudal (显示 CAD 抗体) properties, respectively

  3. current observations of the spatiotemporal disorder of vertebral organogenesis in the Mesp2-null mice provide further insight into the pathogenesis of SCDO and STDO, and the physiological development of the axial skeleton

  4. Data demonstrate that Mesp2 is a novel component involved in the suppression of Notch (显示 NOTCH1 抗体) target genes.

  5. Data propose a novel function of Notch (显示 NOTCH1 抗体) signaling, in which a progressive oscillating wave of Notch (显示 NOTCH1 抗体) activity is translated into the rostral-caudal (显示 CAD 抗体) polarity of a somite by regulating Mesp2 expression in the anterior presomitic mesoderm.

  6. A bHLH-type transcription factor, Mesp2, plays an essential role in somite segmentation in mice.

  7. Data describe the genetic interactions between Dll1 (显示 DLL1 抗体), Dll3 (显示 DLL3 抗体), Mesp2 and Psen1 (显示 PSEN1 抗体), and the roles of Dll1 (显示 DLL1 抗体)- and Dll3 (显示 DLL3 抗体)-Notch (显示 NOTCH1 抗体) pathways, with or without Psen1 (显示 PSEN1 抗体), in rostrocaudal patterning.

  8. Mesp2 is responsible for the rostro-caudal (显示 CAD 抗体) patterning process itself in the anterior presomitic mesoderm, via cellular interaction.

  9. developmental protein "wavefront" is generated by suppression of Notch (显示 NOTCH1 抗体) activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe (显示 LFNG 抗体) gene (Lfng (显示 LFNG 抗体))

  10. Tbx6 (显示 TBX6 抗体) directly binds to the Mesp2 gene upstream region and mediates Notch (显示 NOTCH1 抗体) signaling, and subsequent Mesp2 transcription, in the anterior presomitic mesoderm.

Human Mesoderm Posterior 2 Homolog (Mouse) (Mesp2) interaction partners

  1. MESP2, HES7 and DUSP6 genes may not be involved in the etiopathogenesis of sporadic and non-syndromic CS in Chinese Han population.

  2. Mutated MESP2 causes spondylocostal dysostosis

  3. Mesp1 (显示 MESP1 抗体) is down-regulated in the later stages of development by increasing levels of Mesp2 in the wild-type embryo.

  4. findings suggest a founder-effect mutation in the MESP2 gene as a major cause of the classical Puerto Rican form of spondylothoracic dysostosis/Jarcho-Levin syndrome

Mesp2 抗原简介

蛋白简介

This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

Gene names and symbols associated with Mesp2

  • mesoderm posterior 2 (Mesp2) 抗体
  • mesoderm posterior bHLH transcription factor 2 (Mesp2) 抗体
  • mesoderm posterior bHLH transcription factor 2 (MESP2) 抗体
  • bHLHc6 抗体
  • SCDO2 抗体

Protein level used designations for Mesp2

mesoderm posterior protein 2 , mesoderm posterior 2 , class C basic helix-loop-helix protein 6

GENE ID SPECIES
17293 Mus musculus
293046 Rattus norvegicus
100015370 Monodelphis domestica
145873 Homo sapiens
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