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MXD1 encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. 再加上，我们可以发MXD1 试剂盒 (21) 和 MXD1 蛋白 (6)和数多这个蛋白质的别的产品。
Showing 10 out of 47 products:
Human Monoclonal MXD1 Primary Antibody for ChIP, IP - ABIN5563970
Ullius, Lüscher-Firzlaff, Costa, Walsemann, Forst, Gusmao, Kapelle, Kleine, Kremmer, Vervoorts, Lüscher: The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification. in Nucleic acids research 2014
Study revealed that HIF-1alpha (显示 HIF1A 抗体)-induced Mxd1 contributes to cisplatin-resistance in hypoxic osteosarcoma cells by directly repressing PTEN (显示 PTEN 抗体), which leads to the activation of PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体) antiapoptotic and survival pathway.
the miR (显示 MLXIP 抗体)-382-5p/MXD1 axis plays a critical role in myelopoiesis by affecting the lineage choice of CD34 (显示 CD34 抗体)(+) hematopoietic stem/progenitor cells.
TCP10L stabilizes MAD1 protein level through direct interaction, and they cooperatively regulate cell cycle progression.
down regulation of miR (显示 MLXIP 抗体)-202 increased the expression of its target Mxd1, followed by Mxd1 recruitment to the Sin3A (显示 SIN3A 抗体) repressor complex and through its dimerization with Max, and increased repression of Myc (显示 MYC 抗体)-Max target proteins.
miR-17-92 cluster members miR (显示 MLXIP 抗体)-19a/b facilitated gastric cancer cell migration, invasion and metastasis through targeting the antagonist of c-Myc (显示 MYC 抗体) -- MXD1.
This study suggests that genetic variants of MXD1 may modulate the effect of smoking on carotid plaque burden.
Mad1 gene transfer inhibits the proliferation of human melanoma cells
HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations
MAD1 and Proto-Oncogene (显示 RAB1A 抗体) Proteins c-myc (显示 MYC 抗体) reciprocally regulate ribosomal DNA transcription, providing a mechanism for coordination of ribosome biogenesis and cell growth
c-myc (显示 MYC 抗体) and mad1 can regulate the hTERT transcript in a different manner in hTERT positive cells, but not in normal cells
1,25D and the VDR (显示 CYP27B1 抗体) regulate the c-MYC (显示 MYC 抗体)/MXD1 network to suppress c-MYC (显示 MYC 抗体) function, providing a molecular basis for cancer preventive actions of vitamin D.
Phe-7 is the critical determinant and provides the molecular specificity for the association between Sin3 and Mad in regulating cell growth and differentiation.
Mad1 is a transcriptional repressor of Bcl-6 (显示 BCL6 抗体).
This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
MAX dimerization protein 1
, MAD protein
, max dimerization protein 1
, max dimerizer 1
, MAX-binding protein
, antagonizer of myc transcriptional activity