anti-MAP/microtubule Affinity-Regulating Kinase 4 (MARK4) 抗体

MARK4 encodes a member of the microtubule affinity-regulating kinase family. 再加上,我们可以发MARK4 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MARK4 57787 Q96L34
MARK4 232944 Q8CIP4
MARK4 680407  
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antibodies-online.cn销售最多的anti-MARK4 抗体

Showing 10 out of 120 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IF, ELISA Immunofluorescence analysis of A549 cells, using MARK4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
山羊 非结合性 ELISA, WB ABIN184722 (0.5µg/ml) staining of human prostate lysate (35µg protein in RIPA buffer). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6至7个工作日
$326.89
详细
非结合性 EIA, WB (LEFT)Western blot analysis of anti-MARK4 Pab in mouse liver tissue lysate (35ug/lane). MARK4(arrow) was detected using the purified Pab (1:40dilution). (RIGHT)Western blot analysis of MARK4 (arrow) using rabbit polyclonal hMARK4-R626 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MARK4 gene (Lane 2) 0.4 mL Log in to see 6至8个工作日
$390.50
详细
山羊 非结合性 WB   0.1 mg Log in to see 12至15个工作日
$375.38
详细
非结合性 WB Western blot analysis of anti-MARK4 Pab (ABIN391222) in mouse liver tissue lysate (35 µg/lane). MARK4(arrow) was detected using the purified polyclonal antibody (1:40dilution). Western blot analysis of MARK4 (arrow) using rabbit polyclonal hMARK4-R626 Antibody (ABIN391222).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MARK4 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 EIA, IF, IHC (p) Immunofluorescence analysis of A549 cells, using MARK4 Antibody. The picture on the right is treated with the synthesized peptide. Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 11至13个工作日
$542.85
详细
山羊 非结合性 ELISA, WB 100 μg Log in to see 7至9个工作日
$610.50
详细
非结合性 IC, IF, IHC, WB Immunofluorescent analysis of MARK4 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MARK4 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 IF, IHC (p), ELISA 50 μg Log in to see 12至14个工作日
$541.80
详细
小鼠 非结合性 WB Mouse Mark4 Antibody (C-term)  western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Mark4 antibody detected the Mark4 protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细

通过反应活性、应用领域、克隆类型和共轭标记 MARK4 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-MARK4 抗体

  1. Human Polyclonal MARK4 Primary Antibody for ELISA, WB - ABIN249489 : Kato, Satoh, Okabe, Kitahara, Ono, Kihara, Tanaka, Tsunoda, Yamaoka, Nakamura, Furukawa: Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis. in Neoplasia (New York, N.Y.) 2001 (PubMed)

更多抗MARK4的相互作用对抗体

Human MAP/microtubule Affinity-Regulating Kinase 4 (MARK4) interaction partners

  1. data demonstrate that miR (显示 MLXIP 抗体)-515-5p dramatically inhibits cell migration by directly down-regulating MARK4 expression in two different cancer types

  2. Our results show that MARK4 acts as a negative regulator of the Hippo kinase cassette to promote YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) activity and that loss of MARK4 restrains the tumorigenic properties of breast cancer cells.

  3. Atypical PKC (显示 PRRT2 抗体) phosphorylates serine-threonine residues of MARK4.

  4. Suggest role for polypyrimidine-tract binding protein (显示 PTBP1 抗体) in regulating alternative splicing of MARK4 in gliomas.

  5. MARK4 is a key component in the regulation of microtubule dynamics and has major role in cell cycle progression, particularly at the G1/S transition.

  6. Molecular dynamic simulation data predicted the three dimensional structure for the kinase domain of MARK4 and its structural properties.

  7. A strong and significant elevation of MARK4 expression and MARK4-tau interactions in AD brains correlates with the Braak stages of the disease, suggesting that the MARK4-tau interactions are of functional importance in the progression of AD.

  8. MARK4 is a critical positive regulator of early steps in ciliogenesis.

  9. MARK4 is a new negative regulator of mTORC1

  10. The balance between the MARK4 isoforms is carefully guarded during neural differentiation but may be subverted in gliomagenesis.

Mouse (Murine) MAP/microtubule Affinity-Regulating Kinase 4 (MARK4) interaction partners

  1. PPARgamma (显示 PPARG 抗体) interacted with Mark4 and inhibited the stimulating effect of Mark4 on oxidative stress and inflammation.

  2. MARK4 is a critical positive regulator of early steps in ciliogenesis.

  3. data indicate a key role of MARK4 in energy metabolism, implicating the kinase as a novel drug target for the treatment of obesity and type 2 diabetes.

  4. The balance between the MARK4 isoforms is carefully guarded during neural differentiation but may be subverted in gliomagenesis.

  5. MARK4 is a functional protein kinase (显示 CDK7 抗体) which specifically phosphorylates a cognate peptide substrate for the AMP (显示 TMPRSS5 抗体)-kinase family. On overexpression in heterologous cells functional wild-type protein, but not its kinase-dead mutant, decreased cell viability

MARK4 抗原简介

蛋白简介

This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with MARK4

  • microtubule affinity regulating kinase 4 (MARK4) 抗体
  • MAP/microtubule affinity regulating kinase 4 (Mark4) 抗体
  • microtubule affinity regulating kinase 4 (Mark4) 抗体
  • 2410090P21Rik 抗体
  • C79806 抗体
  • MARK4 抗体
  • MARK4L 抗体
  • MARK4S 抗体
  • Markl1 抗体
  • MARKL1L 抗体
  • PAR-1D 抗体

Protein level used designations for MARK4

MAP/microtubule affinity-regulating kinase 4 , MAP/microtubule affinity-regulating kinase like 1 , MARK4 serine/threonine protein kinase , MAP/microtubule affinity-regulating kinase 4L

GENE ID SPECIES
100070770 Equus caballus
456123 Pan troglodytes
57787 Homo sapiens
232944 Mus musculus
680407 Rattus norvegicus
484449 Canis lupus familiaris
525675 Bos taurus
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