anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) 抗体

Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. 再加上,我们可以发Killer Cell Lectin-Like Receptor Subfamily D, Member 1 蛋白 (17)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
KLRD1 3824 Q13241
KLRD1 16643 O54707
KLRD1 25110 O35778

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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 大鼠 FITC EIA, FACS, IF 0.1 mg Log in to see 29至35个工作日
¥3,279.08
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非结合性 EIA, WB Western blot analysis of KLRD1 Antibody (N-term) in K562 cell line lysates (35ug/lane). KLRD1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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小鼠 大鼠 PE EIA, FACS, IF   50 μg Log in to see 29至35个工作日
¥3,581.80
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小鼠 大鼠 非结合性 EIA, FACS, IF   0.25 mg Log in to see 29至35个工作日
¥3,884.46
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小鼠 非结合性 ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using CD94 mAb against human CD94 (AA: 32-179) recombinant protein. (Expected MW is 42.6 kDa) 100 μL Log in to see 24至29个工作日
¥10,808.99
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小鼠 非结合性 FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of RAJI cells using CD94 mouse mAb (green) and negative control (purple) . 100 μL Log in to see 24至29个工作日
¥10,808.99
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小鼠 Fluorescein FACS Detection of CD94 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 26至31个工作日
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小鼠 大鼠 非结合性 FACS   0.1 mg Log in to see 29至35个工作日
¥2,774.62
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小鼠 非结合性 FACS, IHC (fro), IP   25 μg Log in to see 29至35个工作日
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小鼠 PE FACS 25 Tests Log in to see 29至35个工作日
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通过反应活性、应用领域、克隆类型和共轭标记 KLRD1 抗体

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引用最多的anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 抗体

  1. Mouse (Murine) Monoclonal KLRD1 Primary Antibody for EIA, FACS - ABIN951437 : Toyama-Sorimachi, Taguchi, Yagita, Kitamura, Kawasaki, Koyasu, Karasuyama: Mouse CD94 participates in Qa-1-mediated self recognition by NK cells and delivers inhibitory signals independent of Ly-49. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 3 references for 951437

  2. Mouse (Murine) Monoclonal KLRD1 Primary Antibody for EIA, FACS - ABIN951438 : Meyers, Ryu, Monney, Nguyen, Greenfield, Freeman, Kuchroo: Cutting edge: CD94/NKG2 is expressed on Th1 but not Th2 cells and costimulates Th1 effector functions. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 3 references for 951438

  3. Mouse (Murine) Monoclonal KLRD1 Primary Antibody for EIA, FACS - ABIN951439 : Vance, Kraft, Altman, Jensen, Raulet: Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). in The Journal of experimental medicine 1999 (PubMed)
    Show all 3 references for 951439

  4. Mouse (Murine) Monoclonal KLRD1 Primary Antibody for FACS - ABIN316814 : Vance, Jamieson, Raulet: Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells. in The Journal of experimental medicine 2000 (PubMed)
    Show all 2 references for 316814

  5. Human Monoclonal KLRD1 Primary Antibody for FACS - ABIN4898458 : Hughes, Becknell, McClory, Briercheck, Freud, Zhang, Mao, Nuovo, Yu, Caligiuri: Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the TH 17 cytokine interleukin-22. in Blood 2009 (PubMed)
    Show all 2 references for 4898458

  6. Human Monoclonal KLRD1 Primary Antibody for ELISA, WB - ABIN969032 : Lonigro, Mirabile, Munda, Barchitta, Bottino, Fazzio, Di Cataldo, Agodi, Schilirò: Association between high expression of natural killer related-genes (NCAM/CD94) and early death during induction in children with acute myeloid leukemia. in Leukemia 2008 (PubMed)
    Show all 2 references for 969032

  7. Human Monoclonal KLRD1 Primary Antibody for FACS, ELISA - ABIN969031 : Masilamani, Narayanan, Prieto, Borrego, Coligan: Uncommon endocytic and trafficking pathway of the natural killer cell CD94/NKG2A inhibitory receptor. in Traffic (Copenhagen, Denmark) 2008 (PubMed)
    Show all 2 references for 969031

  8. Human Polyclonal KLRD1 Primary Antibody for EIA, WB - ABIN453720 : Rodríguez, Carretero, Glienke, Bellón, Ramírez, Lehrach, Francis, López-Botet: Structure of the human CD94 C-type lectin gene. in Immunogenetics 1998 (PubMed)
    Show all 2 references for 453720

  9. Human Monoclonal KLRD1 Primary Antibody for FACS, IHC (fro) - ABIN319857 : Aramburu, Balboa, Ramírez, Silva, Acevedo, Sánchez-Madrid, De Landázuri, López-Botet: A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptor-gamma/delta+ T lymphocytes. I. Inhibition of the IL-2-dependent proliferation by anti-Kp43 monoclonal antibody. in Journal of immunology (Baltimore, Md. : 1950) 1990 (PubMed)

更多抗Killer Cell Lectin-Like Receptor Subfamily D, Member 1的相互作用对抗体

Human Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) interaction partners

  1. Collectively, these results provide evidence for the first time that CD94/NKG2C (显示 KLRC2 抗体) is involved in chronic graft-versus-host disease prevention

  2. CD94 and NKG2A (显示 KLRC1 抗体) polymorphisms may contribute to genetic susceptibility to rheumatoid arthritis or affect the response to anti-TNF (显示 TNF 抗体) therapy in patients of Caucasian origin.

  3. Coengagement of inhibitory receptors, either KIR2DL1 (显示 KIR2DL1 抗体) or CD94-NKG2A (显示 KLRC1 抗体), did not inhibit phosphorylation of Stat5 (显示 STAT5A 抗体) but inhibited selectively phosphorylation of Akt (显示 AKT1 抗体) and S6 ribosomal protein (显示 RPS6 抗体).

  4. it is not clear if high expression of CD94 on peripheral blood NK cells is related to abnormal activity of endometrial NK cells.

  5. Data indicate that NKG2 receptor NKG2E (显示 KLRC3 抗体) was capable of associating with CD94 and DAP12 (显示 TYROBP 抗体) but that the complex was retained intracellularly at the endoplasmic reticulum.

  6. Balance between activating NKG2D (显示 KLRK1 抗体), DNAM-1 (显示 CD226 抗体), NKp44 (显示 NCR2 抗体) and NKp46 (显示 NCR1 抗体) and inhibitory CD94/NKG2A (显示 KLRC1 抗体) receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

  7. Data indicate that the expression of KLRD1 (CD94) and NKG2E (KLRC3 (显示 KLRC3 抗体)) was reduced in NK-enriched cells in fulminant type 1 diabetes.

  8. NKG2C (显示 KLRC2 抗体) zygosity influences CD94/NKG2C (显示 KLRC2 抗体) receptor function and the NK-cell compartment redistribution in response to human cytomegalovirus.

  9. Synergistic inhibition of natural killer cells by the nonsignaling molecule CD94.

  10. Studies indicate that HLA-E (显示 HLAE 抗体) interacts with CD94/NKG2 receptors expressed mainly on the surface of natural killer (NK) cells, thus confining its role to the regulation of NK-cell function.

Cow (Bovine) Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) interaction partners

  1. These findings suggest that the CD94/NKG2A (显示 KLRC1 抗体) heterodimers in cattle, in contrast to other species, are binding several different ligands.

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) interaction partners

  1. Segregation of a spontaneous Klrd1 mutation in DBA (显示 RPS19 抗体)/2 mouse substrains

  2. The transmembrane region sequences of CD94 and NKG2 in mouse and rat differ markedly from other mammalian orthologs by the presence of a lysine residue in the transmembrane region.

  3. The complex interplay between various stimuli may account for the variable expression of CD94/NKG2A (显示 KLRC1 抗体) during responses to different pathogens in vivo.

  4. expression of CD94 and its associated NKG2A (显示 KLRC1 抗体), NKG2C (显示 KLRC2 抗体), and NKG2E (显示 KLRC3 抗体) subunits is dispensable for NK cell development, education, and many NK cell functions

  5. show that CD94, a molecule preferentially expressed by NK cells, is essential for the resistance of C57BL/6 mice to mousepox, a disease caused by the Orthopoxvirus ectromelia virus

  6. Implications of CD94 deficiency and monoallelic NKG2A (显示 KLRC1 抗体) expression for natural killer cell development and repertoire formation.

  7. CD94 and NKG2 were both expressed early in NK cell development, sometimes in the absence of NK1.1, with CD94 invariably being expressed at two different levels. IL-4 differentially inhibited the expression of CD94 and Ly49 receptors.

  8. Inhibitory receptor CD94 is expressed on mature fetal thymic and adult epidermal TCR Vgamma3+ lymphocytes.

  9. The acquisition of individual receptor gene expressions during various stages of differentiation in culture from embryonic stem cells to NK cells follows a predetermined order, with the order of receptor acquisition being first CD94.

  10. There is no evidence that CD94 inhibits either the lytic function of lymphocytic choriomeningitis virus-specific T cells or their capacity to produce effector cytokines upon peptide stimulation.

Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) 抗原简介

蛋白简介

Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with KLRD1

  • killer cell lectin-like receptor subfamily D, member 1 (KLRD1) 抗体
  • killer cell lectin-like receptor, subfamily D, member 1 (Klrd1) 抗体
  • Cd94 抗体
  • CD94-B 抗体

Protein level used designations for KLRD1

CD94 antigen , KP43 , NK cell receptor , natural killer cells antigen CD94 , killer cell lectin-like receptor family D member 1 , killer cell lectin-like receptor subfamily D member 1 , Killer cell lectin-like receptor subfamily D member 1 , CD94 antigen (located within the rat natural killer gene complex)

GENE ID SPECIES
3824 Homo sapiens
444877 Bos taurus
611360 Canis lupus familiaris
574145 Macaca mulatta
450156 Pan troglodytes
16643 Mus musculus
25110 Rattus norvegicus
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