Keratin 12 (KRT12) ELISA试剂盒

KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. 再加上,我们可以发Keratin 12 抗体 (45)Keratin 12 蛋白 (8)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
KRT12 3859 Q99456
小鼠 KRT12 KRT12 268482  
大鼠 KRT12 KRT12 360625 Q6IFW5

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0.058 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 7至10个工作日
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Human Keratin 12 (KRT12) interaction partners

  1. we show that the two PAX6 (显示 PAX6 ELISA试剂盒) isoforms differentially and cooperatively regulate the expression of genes specific to the structure and functions of the corneal epithelium, particularly keratin 3 (KRT3) and keratin 12 (KRT12). PAX6 (显示 PAX6 ELISA试剂盒) isoform-a induced KRT3 expression by targeting its upstream region. KLF4 (显示 KLF4 ELISA试剂盒) enhanced this induction. A combination of PAX6 (显示 PAX6 ELISA试剂盒) isoform-b, KLF4 (显示 KLF4 ELISA试剂盒), and OCT4 (显示 POU5F1 ELISA试剂盒) induced KRT12 expression

  2. Combined with an effective delivery vehicle this siRNA approach represents a viable treatment option for prevention of the MECD pathology observed in K12-Leu132Pro heterozygous individuals.

  3. We identified a novel missense mutation of the KRT12 gene in Meesmann corneal dystrophy. The in vivo confocal microscopy examinations revealed previously unreported depth-dependent ultrastructural changes in the living cornea.

  4. Exon sequencing of KRT3 and KRT12 in six affected and eight unaffected individuals did not detect any mutations or nucleotide sequence variants in Meesmann epithelial corneal dystrophy.

  5. The Leu132Pro missense mutation is within the helix-initiation motif of the keratin and is predicted to result in a significant structural change of the K12 protein.

  6. The lead siRNA, with an IC(50) of thirty picomolar, showed no keratin off-target effects or activation of TLR3 (显示 TLR3 ELISA试剂盒) in the concentration ranges tested.

  7. Novel missense mutation within the highly conserved helix-initiation motif of KRT12 causing Meesmann's corneal dystrophy in a German family.

  8. Heterozygous Ala137Pro mutation in keratin 12 gene found in Japanese with Meesmann's corneal dystrophy.

  9. A novel missense mutation (Y429C) in KRT12 lead to MCD in 2 unrelated Taiwanese families.

  10. Mutation in the KRT12 gene is associated with Meesmann corneal dystrophy

Mouse (Murine) Keratin 12 (KRT12) interaction partners

  1. clonal limbal stem cells randomly activate Krt12 alleles in the process of terminal differentiation in cornea

Keratin 12 (KRT12) 抗原简介

Antigen Summary

KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy.

Gene names and symbols associated with Keratin 12 (KRT12) ELISA试剂盒

  • zgc:92533 (zgc:92533) 抗体
  • keratin 12 (KRT12) 抗体
  • keratin 12 (krt12) 抗体
  • keratin 12 (Krt12) 抗体
  • keratin K12 (LOC100009289) 抗体
  • AI835216 抗体
  • fb05e09 抗体
  • K12 抗体
  • Ka12 抗体
  • Krt-12 抗体
  • Krt1-12 抗体
  • wu:fa91b04 抗体
  • wu:fa97a07 抗体
  • wu:fb05e09 抗体
  • xk81b2 抗体

Protein level used designations for Keratin 12 (KRT12) ELISA试剂盒

keratin 12 , fa97a07 , krtt1c19a , cytokeratin , type I keratin , keratin 12 (Meesmann corneal dystrophy) , CK-12 , cytokeratin-12 , keratin, type I cytoskeletal 12 , keratin-12 , Keratin, type I cytoskeletal 12 (Cytokeratin 12) , keratin complex 1, acidic, gene 12 , K12 , keratin K12 , type I keratin KA12 , keratin, type I cytoskeletal 47 kDa , B2 keratin

GENE ID SPECIES
445051 Danio rerio
100034663 Canis lupus familiaris
100144436 Xenopus (Silurana) tropicalis
468241 Pan troglodytes
3859 Homo sapiens
268482 Mus musculus
360625 Rattus norvegicus
398464 Xenopus laevis
100009289 Oryctolagus cuniculus
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