Jumonji Domain Containing 6 (JMJD6) ELISA试剂盒

JMJD6 encodes a nuclear protein with a JmjC domain. 再加上,我们可以发Jumonji Domain Containing 6 抗体 (116)Jumonji Domain Containing 6 蛋白 (10)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
JMJD6 23210 Q6NYC1
JMJD6 107817 Q9ERI5
JMJD6 360665 Q6AYK2

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Human Jumonji Domain Containing 6 (JMJD6) interaction partners

  1. miR (显示 MLXIP ELISA试剂盒)-770 acted on a tumor suppressor by binding to the 3'UTR (显示 UTS2R ELISA试剂盒) of JMJD6 and downregulated its expression in NSCLC cells; this study also demonstrated that JMJD6 played as an oncogene (显示 RAB1A ELISA试剂盒) in NSCLC cells

  2. JMJD6 regulated a large set of alternative splicing events, and importantly, its regulated splicing events were significantly overlapped those controlled by U2AF65 (显示 U2AF59 ELISA试剂盒).

  3. AcK27-HOXB9 (显示 HOXB9 ELISA试剂盒) suppresses the transcription of its target gene Jumonji domain-containing protein 6 (JMJD6) by direct occupying the promoter of JMJD6 gene.

  4. These findings provide evidence that JMJD6 may play a role in regulating the production of sFLT-1 in the preeclamptic placenta. Decreased placental JMJD6 expression may be an important component to the pathophysiology of preeclampsia.

  5. Study identified a novel epigenetic mechanism showing how JMJD6 cooperates with Myc (显示 MYC ELISA试剂盒) during oncogenic transformation. Combined high expression of Myc (显示 MYC ELISA试剂盒) and JMJD6 confers a more aggressive phenotype in mouse and human tumors.

  6. Our studies identify JMJD6 as a molecular determinant of cancer stem cell phenotype

  7. Although JMJD6 displays anti-tumoral properties in cell lines, its expression in breast tumours may be a marker of poor prognosis, suggesting that its function could be altered in breast cancer

  8. The expression of JMJD6 was reduced in T lymphocytes in chronic hepatitis B.

  9. A novel role for JMJD6 as an oxygen sensor in the human placenta, and alterations in the JMJD6-VHL (显示 VHL ELISA试剂盒)-HIF1A (显示 HIF1A ELISA试剂盒) feedback loop may indirectly contribute to elevated HIF1A (显示 HIF1A ELISA试剂盒) found in preeclampsia.

  10. JMJD6 is a potential biomarker for colon cancer aggressiveness and a potential target for colon cancer intervention.

Mouse (Murine) Jumonji Domain Containing 6 (JMJD6) interaction partners

  1. TEC-specific deletion of Jmjd6 exacerbates development of autoimmune diabetes in a mouse model, which express both ovalbumin (OVA) under the control of the rat insulin gene promoter and OT-I T cell receptor specific for OVA peptide bound to major histocompatibility complex class I K(b) molecules.

  2. Although Jmjd6 deficiency does not affect abundance of Aire (显示 AIRE ELISA试剂盒) transcript, the intron 2 of Aire (显示 AIRE ELISA试剂盒) gene is not effectively spliced out in the absence of Jmjd6, resulting in reduction of mature Aire (显示 AIRE ELISA试剂盒) protein and spontaneous multi-organ autoimmunity in mice.

  3. The results indicate dual roles for JMJD6 in promoting adipogenic gene expression program by post-transcriptional regulation of C/EBPbeta (显示 CEBPB ELISA试剂盒) and C/EBPdelta (显示 CEBPD ELISA试剂盒) and direct transcriptional activation of Ppargamma2 (显示 PPARG ELISA试剂盒) and Cebpalpha during adipocyte differentiation.

  4. histones are additional substrates of JMJD6 in vivo. Because 5-hydroxylation of lysyl residues inhibited N-acetylation and N-methylation by an acetyltransferase and a methyltransferase

  5. confirmed that Jmjd6 forms multimers and showed that nuclear localization of the protein involves association with a nucleic acid matrix

  6. protein kinase C beta (显示 PRKCB ELISA试剂盒) activation is dependent upon phosphatidylserine receptor action

  7. data demonstrate a critical role for PSR in early stages of mammalian organogenesis and suggest that this receptor may be involved in respiratory distress syndromes and congenital brain malformations

  8. during embryonic development, phosphatidylserine receptor-mediated apoptotic cell uptake is required for definitive erythropoiesis and T lymphopoiesis, independently of the prevention of inflammatory responses

  9. Ptdsr is localized in the cell nucleus via multiple nuclear localization signals.

  10. Ptdsr is essential for the development and differentiation of multiple organs during embryogenesis but not for apoptotic cell clearance.

Zebrafish Jumonji Domain Containing 6 (JMJD6) interaction partners

  1. results suggest that YY1a (显示 YY1 ELISA试剂盒) regulates PS receptor expression that linked to function of PSR-phagocyte mediated apoptotic cell engulfment during development

  2. PSR-dependent system in zebrafish embryos that engulfs apoptotic cells mediated by PSR-phagocytes during development, with the system assuming an important role in the normal development of tissues such as the brain, heart, notochord and somite

Cow (Bovine) Jumonji Domain Containing 6 (JMJD6) interaction partners

  1. JMJD6 contributes to foot-and-mouth disease virus infectivity and may be a previously unidentified foot-and-mouth disease receptor.

  2. Demethylated RHA bound JMJD6 monomer during foot-and-mouth disease virus infection.

Jumonji Domain Containing 6 (JMJD6) 抗原简介

Antigen Summary

This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells\; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with JMJD6

  • jumonji domain containing 6 (LOC100230335) 抗体
  • phosphatidylserine receptor (PSR) 抗体
  • phosphatidylserine receptor (AaeL_AAEL008084) 抗体
  • phosphatidylserine receptor (AaeL_AAEL013254) 抗体
  • phosphatidylserine receptor (AaeL_AAEL013632) 抗体
  • phosphatidylserine receptor (CpipJ_CPIJ004848) 抗体
  • phosphatidylserine receptor (CpipJ_CPIJ019866) 抗体
  • jumonji domain containing 6 (jmjd6) 抗体
  • jumonji domain containing 6 (JMJD6) 抗体
  • jumonji domain containing 6 (Jmjd6) 抗体
  • jumonji domain containing 6 (jmjd6-a) 抗体
  • jumonji domain containing 6 (jmjd6-b) 抗体
  • 5730436I23Rik 抗体
  • cg5383 抗体
  • D11Ertd195e 抗体
  • GB15204 抗体
  • jmjd6 抗体
  • mKIAA0585 抗体
  • psr 抗体
  • PtdSerR 抗体
  • Ptdsr 抗体
  • ptdsr1 抗体
  • zfpsr 抗体
  • zgc:66264 抗体

Protein level used designations for JMJD6

jumonji domain containing 6 , phosphatidylserine receptor , Histone arginine demethylase JMJD6 , bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 , jmjC domain-containing protein 6 , jumonji domain-containing protein 6 , lysyl-hydroxylase JMJD6 , peptide-lysine 5-dioxygenase JMJD6 , histone arginine demethylase JMJD6 , apoptotic cell clearance receptor PtdSerR , bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-A , histone arginine demethylase JMJD6-A , jmjC domain-containing protein 6-A , jumonji domain-containing protein 6-A , lysyl-hydroxylase JMJD6-A , peptide-lysine 5-dioxygenase JMJD6-A , phosphatidylserine receptor-A , protein PTDSR-A , bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B , histone arginine demethylase JMJD6-B , jmjC domain-containing protein 6-B , jumonji domain-containing protein 6-B , lysyl-hydroxylase JMJD6-B , peptide-lysine 5-dioxygenase JMJD6-B , phosphatidylserine receptor-B , protein PTDSR-B , protein PTDSR

GENE ID SPECIES
100230335 Taeniopygia guttata
411069 Apis mellifera
5570116 Aedes aegypti
5577546 Aedes aegypti
5578311 Aedes aegypti
6036446 Culex quinquefasciatus
6054124 Culex quinquefasciatus
548957 Xenopus (Silurana) tropicalis
100173544 Pongo abelii
23210 Homo sapiens
107817 Mus musculus
266962 Danio rerio
444377 Xenopus laevis
417355 Gallus gallus
508343 Bos taurus
360665 Rattus norvegicus
380206 Xenopus laevis
483335 Canis lupus familiaris
468338 Pan troglodytes
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