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The protein encoded by IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. 再加上，我们可以发IL18RAP 抗体 (118) 和 IL18RAP 蛋白 (24)和数多这个蛋白质的别的产品。
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These findings suggested that IL-18RAP rs917997, IL-32 (显示 IL32 ELISA试剂盒) rs2015620, IL-22 (显示 IL22 ELISA试剂盒) rs1179251, and interactions between these polymorphisms and H. pylori infection were associated with risks of gastric lesions
some SNPs of ST2-IL18R1-IL18RAP gene cluster might increase the risk of susceptibility of Graves' disease (GD) and Hashimoto's thyroiditis (HT) in Chinese Han population.
This meta-analysis provides robust estimates that IL18RAP rs917997 and chemokine (C-C motif) receptor 3 (显示 CCR3 ELISA试剂盒) rs6441961 are potential risk factors for celiac disease in European populations.
results demonstrate clear functional consequences of the rs917997 risk polymorphism; this polymorphism leads to a loss-of-function through decreased IL-18RAP, IL-18R1 (显示 IL18R1 ELISA试剂盒), and IL-1R1 protein expression, which impairs autocrine IL-18 (显示 IL18 ELISA试剂盒) and IL-1 (显示 IL1A ELISA试剂盒) signaling
The SNP modified IL18RAP surface protein expression by NK cells.
Data indicate that MyD88 works together with the IL-1/IL-18 receptors, can interact with two distinct sorting adaptors, TRAM and Mal, in a conserved manner.
Data suggest that IL-18RAP and IL-18R1 (显示 IL18R1 ELISA试剂盒) single-nucleotide polymorphisms identify African-American infants at risk for bronchopulmonary dysplasia.
IL-18 (显示 IL18 ELISA试剂盒), IL-18 receptor alpha (显示 IL18R1 ELISA试剂盒), and CD48 (显示 CD48 ELISA试剂盒) complex formation via glycosylphosphatidylinositol anchor glycan triggers binding to IL-18 receptor beta, and thereby induces intracellular signal transduction and IFN-gamma (显示 IFNG ELISA试剂盒) production.
Truncated forms of IL-18RAP may be involved in the complex mechanism of IL-18 (显示 IL18 ELISA试剂盒) activity regulation.
Variations in IL18RAP is associated with celiac disease
Our data highlight the considerable complexity of the IL-18 (显示 IL18 ELISA试剂盒) regulation activity in the mouse brain and further support an important central role for IL-18 (显示 IL18 ELISA试剂盒).
This study demonstrates that IL-18 (显示 IL18 ELISA试剂盒) signals are abolished in accessory protein-like (AcPL)-deficient mice and cells, and suggests that AcPL is a critical and specific cell surface receptor required for IL-18 (显示 IL18 ELISA试剂盒) signaling.
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
interleukin 18 receptor accessory protein
, IL-18 receptor beta
, interleukin-18 receptor accessory protein-like
, CD218 antigen-like family member B
, IL-18 receptor accessory protein
, interleukin-1 receptor 7
, interleukin-18 receptor accessory protein
, interleukin-18 receptor beta
, AcPL accessory protein-like)