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ICAM4 encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. 再加上，我们可以发ICAM4 抗体 (74) 和 ICAM4 蛋白 (13)和数多这个蛋白质的别的产品。
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the effect of modulation of the cAMP-PKA-dependent pathway on ICAM-4 receptor activation
Cytometry analysis evidenced a specific expression profile on reticulocytes of SCA infants, with notably an increased expression of the adhesion molecules Lu/BCAM (显示 BCAM ELISA试剂盒), ICAM-4 and LFA-3, both in percentage of positive cells and in surface density.
ICAM-1 (显示 ICAM1 ELISA试剂盒) and ICAM-4 play roles in host cell invasion by M. tuberculosis and P. falciparum, respectively.
Seven variant ICAM4 alleles were found, distinct from the wild-type ICAM4 allele (GenBank KF712272), known as LW*05 and encoding LW(a) .
Data from differentiating cultured erythroid precursor cells suggest that RhAG (Rh-associated glycoprotein (显示 RHAG ELISA试剂盒)) knockdown abolishes Rh blood group (显示 DARC ELISA试剂盒) expression (ICAM4; RhoD [ras homolog family member D]; CD47 Rh-related antigen (显示 CD47 ELISA试剂盒)) in erythroid cells.
Erythrocyte plasma membrane-bound ERK1/2 (显示 MAPK1/3 ELISA试剂盒) activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium.
In a transgenic mouse model of sickle cell disease ICAM-4 is implicated in abnormal adhesiveness of erythrocytes to endothelium.
ICAM-4 as the first red blood cells protein ligand of platelets that may have relevant physiological significance
binds to the I domains of the CD11a (显示 ITGAL ELISA试剂盒)/CD18 (显示 ITGB2 ELISA试剂盒) and CD11b/CD18 (显示 ITGAM ELISA试剂盒) leukocyte integrins
12 single amino-acid changes in ICAM4 affected the interaction of ICAM-4 with alpha(V) integrins
A novel second splice cDNA encodes an ICAM-4 isoform lacking the membrane-spanning domain. Erythroblasts express both isoforms. This new isoform, ICAM (显示 ICAM1 ELISA试剂盒)-4S, may modulate membrane-associated ICAM-4 binding & regulate erythroblast molecular attachments.
ICAM-4 is critical in erythroblastic island formation via ICAM-4/alpha(V) adhesion
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100\; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
, LW blood group protein
, Landsteiner-Wiener blood group antigen a
, Landsteiner-Wiener blood group glycoprotein
, intercellular adhesion molecule 4
, intercellular adhesion molecule 4 (LW blood group)
, Landsteiner-Wiener blood group protein
, intercellular adhesion molecule 4, Landsteiner-Wiener blood group
, LW glycoprotein