anti-Hemoglobin, gamma A (HBG1) 抗体

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. 再加上,我们可以发HBG1 蛋白 (12)HBG1 试剂盒 (9)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HBG1 94164  
HBG1 3047 P69891
HBG1    

antibodies-online.cn销售最多的anti-HBG1 抗体

Showing 10 out of 39 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB HBG1 Antibody (Center) (ABIN657619) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the HBG1 antibody detected the HBG1 protein (arrow). 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (33.04 KDa) . 50 μL Log in to see 29至34个工作日
¥2,071.99
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小鼠 非结合性 ELISA Detection limit for recombinant GST tagged HBG1 is 3 ng/ml as a capture antibody. 100 μg Log in to see 29至34个工作日
¥3,169.73
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非结合性 WB Western blot analysis of HBG1 using rabbit polyclonal HBG1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HBG1 gene. Western blot analysis in K562 cell line lysates (35ug/lane). 400 μL Log in to see 24至29个工作日
¥5,032.78
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小鼠 非结合性 ELISA   100 μg Log in to see 29至35个工作日
¥5,401.63
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HRP ELISA, IHC (p)   100 μg Log in to see 29至35个工作日
¥5,813.45
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Biotin ELISA, IHC (p)   100 μg Log in to see 29至35个工作日
¥5,813.45
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FITC ELISA, IHC (p)   100 μg Log in to see 29至35个工作日
¥5,813.45
详细
非结合性 WB   200 μL Log in to see 29至35个工作日
¥7,803.92
详细
Biotin WB   200 μL Log in to see 29至35个工作日
¥9,863.01
详细

通过反应活性、应用领域、克隆类型和共轭标记 HBG1 抗体

特性 应用范围 宿主 克隆类型 标记
Rat (Rattus)


Human , ,
,
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Mouse (Murine)


引用最多的anti-HBG1 抗体

  1. Human Polyclonal HBG1 Primary Antibody for WB - ABIN657619 : Zhou, Liu, Sun, Pawlik, Townes: KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching. in Nature genetics 2010 (PubMed)

  2. Human Polyclonal HBG1 Primary Antibody for ELISA, WB - ABIN561232 : Lee, Kim, Byrnes, de Vasconcellos, Noh, Rabel, Meier, Miller: A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors. in PLoS ONE 2013 (PubMed)

更多抗HBG1的相互作用对抗体

Human Hemoglobin, gamma A (HBG1) interaction partners

  1. Introduction of the British HPFH mutation into the fetal globin promoter in a human cell model causes elevated fetal globin expression. The British HPFH mutation creates a de novo binding site both in vitro and in vivo for the potent erythroid activator KLF1 (显示 KLF1 抗体).

  2. A Ly1 antibody reactive (LYAR)-binding motif disruptive regulatory single-nucleotide polymorphisms rs368698783 (G/A) from LD block 5 in the proximal promoter of hemoglobin subunit gamma 1 (HBG1) was found to be a significant predictor for beta-thalassemia clinical severity.

  3. Study found a novel polymorphism of the A-gamma-globin gene in four families with b0-thalassemia and high levels of HbF expression. Additionally, evidence suggesting that the Ac-globin gene +25(G-A) polymorphism decreases the efficiency of the interaction between this sequence and specific DNA binding protein (显示 UBE2V1 抗体) complexes.

  4. These data confirm the regulatory role of the HBG1: g.-225_-222 region that exerts its effect under conditions of erythropoietic stress characteristic for beta-thal patients.

  5. results suggest that KLF1 directly regulates the beta-globin gene, but probably has less direct impact on expression of the gamma-globin gene in fetal erythroblasts

  6. Data show that the ancestral allele C at rs2855126, located upstream of gamma-globin (HBG1) is associated with increased serum uric acid levels.

  7. analysis of a point mutation that increases fetal globin expression through de novo recruitment of the activator TAL1 to promote chromatin looping of distal enhancers to the modified gamma-globin promoter

  8. a successful induction of gamma-globin includes a reduction in BCL11A (显示 BCL11A 抗体), KLF1 (显示 KLF1 抗体) and TAL1 (显示 TAL1 抗体) expression.

  9. This report we discusses the molecular characteristics and diagnostic criteria of a new (A)gamma chain variant that was detected during newborn screening and named Hb F-Sykesville MD [(A)gamma113(G15 (显示 RBM5 抗体))Val --> Ile; HBG1: c.340G>A].

  10. Results indicate that compound II induces the gamma globin gene in hydroxyurea (HU)-resistant primary adult erythroid cells and suggest potenetial therapy for sickle cell disease (SCD (显示 SCD 抗体)) and severe beta-thalassemias.

HBG1 抗原简介

蛋白简介

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene names and symbols associated with anti-Hemoglobin, gamma A (HBG1) 抗体

  • hemoglobin subunit gamma-1-like (LOC100438895) 抗体
  • hemoglobin, gamma A (Hbg1) 抗体
  • hemoglobin, gamma A (HBG1) 抗体
  • hemoglobin, gamma G (HBG2) 抗体
  • Hbb-y 抗体
  • Hbe1 抗体
  • HBG1 抗体
  • HBG2 抗体
  • HBGA 抗体
  • HBGR 抗体
  • HSGGL1 抗体

Protein level used designations for anti-Hemoglobin, gamma A (HBG1) 抗体

epsilon 3 globin , hemoglobin Y beta-like embryonic chain , hemoglobin Y, beta-like embryonic chain , hemoglobin, epsilon 1 , hemoglobin, gamma A , A-gamma globin , gamma A hemoglobin , gamma globin , gamma-1-globin , hb F Agamma , hemoglobin gamma-1 chain , hemoglobin gamma-a chain , hemoglobin subunit gamma-1 , hemoglobin, gamma, regulator of , epsilon-globin , hemoglobin, gamma G

GENE ID SPECIES
100438895 Pongo abelii
94164 Rattus norvegicus
100137314 Papio anubis
3047 Homo sapiens
450979 Pan troglodytes
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