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GTF2B encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. 再加上，我们可以发General Transcription Factor IIB 抗体 (123) 和 General Transcription Factor IIB 蛋白 (23)和数多这个蛋白质的别的产品。
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binding of specific DNA sequences changes the protein structure and dynamics, and TFIIB may exist in two conformational states
The role of zinc at Cys3His1 binding site in the absence of TFIIB protein folding
these results establish a new paradigm for TFIIB functionality in human gene expression, which when downregulated has potent anti-viral effects.
Association of the winged helix motif of the TFIIEalpha subunit of TFIIE with either the TFIIEbeta subunit or TFIIB distinguishes its functions in transcription.
TFIIB was involved in the proliferation and growth of HCC (显示 FAM126A ELISA试剂盒) cells.
a mode of phospho-TFIIB-independent transcriptional regulation that prioritizes the transcription of p53 (显示 TP53 ELISA试剂盒)-target genes during cellular stress.
Data show that TFIIF (显示 GTF2F1 ELISA试剂盒) has an important role in stabilizing TFIIB within the PIC and after transcription initiates.
a six-amino acid human TFIIB tip region is needed for appropriate levels of serine 5 C-terminal domain phosphorylation and mRNA capping and for retention of the required elongation factor (显示 TSFM ELISA试剂盒) TFIIF (显示 GTF2F1 ELISA试剂盒).
phosphorylation of TFIIB at serine 65 is a critical event in transcription that links the gene promoter and terminator and triggers initiation by RNA pol II
interaction with vitamin D receptor (显示 VDR ELISA试剂盒) helix H10 (显示 H1F0 ELISA试剂盒) residues
by acutely targeting TFIIB, we were able to inhibit selectively the former set of genes and ameliorate pressure overload hypertrophy.
TFIIB co-localizes and interacts with alpha-tubulin (显示 TUBA4A ELISA试剂盒) during oocyte meiosis in the mouse and depletion of TFIIB causes arrest of subsequent embryo development.
Study suggest that components of the transcription machinery decreased in accordance with cell differentiation and that TFIIB is specifically and rapidly degraded by the ubiquitin-proteasome pathway.
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
, transcription factor IIB
, transcription initiation factor iib
, transcription initiation factor IIB
, transcription initiation factor iiB
, Transcription initiation factor IIB
, hypothetical protein
, general transcription factor IIB
, general transcription factor TFIIB
, RNA polymerase II transcription factor IIB
, RNA polymerase II alpha initiation factor