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CCL22 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. 再加上，我们可以发CCL22 抗体 (242) 和 CCL22 蛋白 (61)和数多这个蛋白质的别的产品。
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Human CCL22 ELISA Kit for Sandwich ELISA - ABIN625044
Shi, Song, Xiong, Cao, Liao, Ma, Zhang, Zeng, Liu, Wang, Cui, Huang, Liu: Disease-specific T-helper cell polarizing function of lesional dendritic cells in different types of chronic rhinosinusitis with nasal polyps. in American journal of respiratory and critical care medicine 2014
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Human CCL22 ELISA Kit for Sandwich ELISA - ABIN365803
García, Cidoncha, Bote, Hinchado, Ortega: Altered profile of chemokines in fibromyalgia patients. in Annals of clinical biochemistry 2014
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Human CCL22 ELISA Kit for Sandwich ELISA - ABIN411323
Godiska, Chantry, Raport, Sozzani, Allavena, Leviten, Mantovani, Gray: Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. in The Journal of experimental medicine 1997
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These results showed that the higher levels of CXCL10 (显示 CXCL10 ELISA试剂盒), CCL20 (显示 CCL20 ELISA试剂盒) and CCL22 were associated with ischemic heart disease. The serum levels of chemokines may influence by the certain traditional risk factors of IHD and some studied SNPs, but did not influence by treatment and gender of patients.
CCL22 plays an important role in supporting gastric cancer development presumably by increasing the percentage of regulatory T cells in the tumor microenvironments. CCL22 levels in sera have a predictive value for gastric cancer peritoneal metastasis and the early recurrence.
The CCL22-mediated enhancement of antitumor responses is however not due to conversion, but rather to redirection of existing regulatory T cells to the site of cutaneous overexpression.
CCL22 and IL-37 with a co-localization in non-small cell lung cancer A549 cells inhibited the proliferation and epithelial-mesenchymal transition process
Data suggest that Th1 (显示 TH1L ELISA试剂盒) (IFN-gamma (显示 IFNG ELISA试剂盒)-inducible protein-10 IP-10/CXCL10 (显示 CXCL10 ELISA试剂盒)) and Th2 (thymus and activation regulated chemokine TARC/CCL17 (显示 CCL17 ELISA试剂盒)) and (macrophage derived chemokine MDC/CCL22) cooperatively play a role in the development of ankylosing spondylitis (AS).
Our results demonstrate that CCL22 is expressed in human placenta. Decidual expression was only observed in miscarriage conditions and correlates with Treg infiltration.
Distinctive Treg associated CCR4 (显示 CCR4 ELISA试剂盒)-CCL22 expression profile with altered frequency of Th17/Treg cell in the immunopathogenesis of Pemphigus Vulgaris (显示 DSG3 ELISA试剂盒).
type I IFN blocks the regulatory T cell-attracting chemokine (显示 CCL1 ELISA试剂盒) CCL22 and thus helps limit the recruitment of regulatory T cells to tumors
First-episode psychosis patients had higher serum CCL22, which decreased substantially following antipsychotic treatment.
Elevated levels of CCL22 found in the ascites could create a chemokine (显示 CCL1 ELISA试剂盒) gradient aiding in Treg cells migration. Increased Tregs percentage in the local microenvironment of ovarian cancer might be an important mechanism of immunosuppression.
Intratumoral administration of anti-CCL22 antibody inhibited B16F10 melanoma growth.
this study shows that intravenous injection of apoptotic cells induces a subsequent increase in CCL22 expression and CCR4 (显示 CCR4 ELISA试剂盒)+ Treg cells, which contribute to the maintenance of immune homeostasis at least partially by splenic CD8alpha+ CD103 (显示 ITGAE ELISA试剂盒)+ dendritic cells
CCL22-specific antibodies reveal that engagement of two distinct binding domains on CCL22 is required for CCR4 (显示 CCR4 ELISA试剂盒)-mediated function.
CCL22 was localised mainly on the cell surface and or in the cytoplasm. Within sections of omental milky spot micrometastases, CCR4 (显示 CCR4 ELISA试剂盒) was recognised on or in gastric cancer cells, constituent cells milky spots, blood cells and blood endothelial cells
results show that the IL-4 (显示 IL4 ELISA试剂盒)/CCL22/CCR4 (显示 CCR4 ELISA试剂盒) axis is involved in the migration of Tregs to osteolytic lesion sites, and attenuates development of lesions by inhibiting inflammatory migration and the production of proinflammatory and osteoclastogenic mediators
CCL22 has a role in Treg skin homing to suppress depigmentation
CCL22 is a novel mediator of lung inflammation following hemorrhage and resuscitation
The immunomodulatory properties of CCL22 could be harnessed for prevention of graft rejection and type 1 diabetes as well as other autoimmune disorders.
Data indicate macrophage-derived chemokine CCL22 as an adjuvant could enhance the immune protective effect of NTHi-P6 protein vaccine to an extent.
islet expression of CCL22 recruits Tregs and attenuates autoimmune destruction of beta cell
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.
chemokine (C-C motif) ligand 22
, C-C motif chemokine 22
, CC chemokine STCP-1
, macrophage-derived chemokine
, small inducible cytokine A22
, small inducible cytokine subfamily A (Cys-Cys), member 22
, small-inducible cytokine A22
, stimulated T cell chemotactic protein 1
, stimulated T-cell chemotactic protein 1
, small inducible cytokine subfamily A (Cys-Cys) member 22
, CC chemokine ABCD-1
, SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED)
, activated B and dendritic cell-derived
, dendritic cell and B cell derived chemokine
, small inducible cytokine subfamily A, member 22
, small inducible cytokine subfamily A22