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CD320 encodes the transcobalamin receptor that is expressed at the cell surface. 再加上，我们可以发CD320 抗体 (38) 和 CD320 蛋白 (23)和数多这个蛋白质的别的产品。
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This study evaluated the role of transcobalamin (TC), the transcobalamin receptor (CD320) , and megalin (显示 LRP2 ELISA试剂盒) in various tissues during pregnancy.
CD320 role in the hippocampal long-term potentiation and the hippocampal pyramidal neurons.
Severe cobalamin depletion in the central nervous system (CNS) after birth in TCblR knockouts indicates that TCblR is the only receptor responsible for cobalamin uptake in the CNS
In vivo, endogenous PCSK9 (显示 PCSK9 ELISA试剂盒) regulates VLDLR (显示 VLDLR ELISA试剂盒) protein levels and triglyceride accumulation in adipose tissue.
Diabetic rats showed severe hyperlipidemia on d 21 and 28, with a dramatic decline in VLDL-R (显示 VLDLR ELISA试剂盒) protein in skeletal muscle (>90%), heart (approximately 50%) and a loss of adipose tissues itself.
Reelin (显示 RELN ELISA试剂盒) binds several receptors, including the VLDL receptor (显示 VLDLR ELISA试剂盒) in cultured hippocampus neurons.
VLDL and LDL lowering by gene transfer of the VLDL receptor (显示 VLDLR ELISA试剂盒) combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor (显示 LDLR ELISA试剂盒)-deficient mice
These data demonstrate a cell-autonomous function of ApoER2 (显示 LRP8 ELISA试剂盒), and most likely VLDLR (显示 VLDLR ELISA试剂盒) and Dab1 (显示 DAB1 ELISA试剂盒), in postnatal migration of neuroblasts in the forebrain, which is suggested to depend on ligands other than Reelin (显示 RELN ELISA试剂盒).
The high affinity of apoE4 to the LDLR (显示 LDLR ELISA试剂盒) enhances VLDL sequestration on the hepatocyte surface but delays their internalization.
Data show that thrombospondin-1 (THBS-1 (显示 THBS1 ELISA试剂盒)) is a novel physiological ligand for ApoER2 (显示 LRP8 ELISA试剂盒) and VLDLR (显示 VLDLR ELISA试剂盒), and that lack of THBS-1 (显示 THBS1 ELISA试剂盒) results in anatomical abnormalities of the RMS and leads to a reduction of postnatal neuronal precursors entering the OB.
Although not significant when corrected for multiple testing, eight single nucleotide polymorphisms (SNPs) in two genes, transcobalamin II (TCN2 (显示 TCN2 ELISA试剂盒)) and the transcobalamin II (显示 TCN2 ELISA试剂盒)-receptor (TCblR), were found to influence several clinical traits of cobalamin deficiency.
The soluble transcobalamin receptor is present in cerebrospinal fluid and correlates to dementia-related biomarkers tau proteins and amyloid-beta.
Transcobalamin II (TCN2 (显示 TCN2 ELISA试剂盒) 67A>G and TCN2 (显示 TCN2 ELISA试剂盒) 776C>G) and transcobalamin II (显示 TCN2 ELISA试剂盒) receptor (TCblR 1104C>T) polymorphisms in Korean patients with idiopathic recurrent spontaneous abortion
Data indicate that only the extracellular region (aa 32-229) of TCblR/CD320 is needed for transcobalamin-cobalamin (TC-Cbl (显示 CBL ELISA试剂盒)) binding.
Proliferating cancer cells express measurable levels of TCII (显示 TCN2 ELISA试剂盒) and TCII (显示 TCN2 ELISA试剂盒)-R.
TCblr SNP were associated with omphalocele suggests that disruption of methylation reactions, in which folate, vitamin B12 (显示 NDUFB3 ELISA试剂盒), and homocysteine play critical parts, may be a risk factor for omphalocele.
Our data suggest that variation in TCblR plays a role in neural tube defect risk and that these variants may modulate cobalamin metabolism.
the cell cycle associated expression of TCblR appears to be tightly regulated in synchrony with the proliferative phase of the cell cycle.
Analysis of TCblR/CD320, the gene for the receptor for cellular uptake of transcobalamin-bound cobalamin, identified a homozygous single codon deletion, c.262_264GAG (p.E88del), resulting in the loss of a glutamic acid residue.
Confocal microscopy of tonsil sections revealed co-localization of CD320 with CD19 (显示 CD19 ELISA试剂盒) and CD38 but not with CD3 (显示 CD3 ELISA试剂盒) indicating that germinal center B cells expressed CD320 in addition to follicular dendritic cells.
This gene encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin (vitamin B12), and is involved in B-cell proliferation and immunoglobulin secretion. Mutations in this gene are associated with methylmalonic aciduria. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, putative VLDL lipoprotein receptor
, transcobalamin receptor
, 8D6 antigen
, CD320 antigen
, FDC-signaling molecule 8D6