B-Cell Linker (BLNK) ELISA试剂盒

BLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. 再加上,我们可以发B-Cell Linker 抗体 (212)B-Cell Linker 蛋白 (13)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
BLNK 17060 Q9QUN3
BLNK 29760 Q8WV28
BLNK 499356 Q4KM52
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12至14个工作日
$638.00
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小鸡 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12至14个工作日
$715.00
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Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12至14个工作日
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37.5 pg/mL 62.5-4000 pg/mL   96 Tests Log in to see 12至14个工作日
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豚鼠 0.469 ng/mL 0.781-50 ng/mL   96 Tests Log in to see 12至14个工作日
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大鼠 1.0 pg/mL 250-5000 pg/mL   96 Tests Log in to see 15至18个工作日
$707.14
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小鼠 1.0 pg/mL 250-5000 pg/mL   96 Tests Log in to see 15至18个工作日
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1.0 pg/mL 250-5000 pg/mL   96 Tests Log in to see 15至18个工作日
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  2 x 96 Tests Log in to see 6 Days
$597.40
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1.0 pg/mL 250-5000 pg/mL   96 Tests Log in to see 15至18个工作日
$707.14
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适于 B-Cell Linker 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) B-Cell Linker (BLNK) interaction partners

  1. The pre-B-cell receptor (pre-BCR (显示 BCR ELISA试剂盒)) signaling molecules BLNK, BTK (显示 BTK ELISA试剂盒) and BANK1 (显示 BANK1 ELISA试剂盒) were positively regulated by the ZFP521 gene, leading to enhancement of the pre-BCR (显示 BCR ELISA试剂盒) signaling pathway.

  2. Authors demonstrate leukemogenicity of PAX5 (显示 PAX5 ELISA试剂盒)-PML (显示 PML ELISA试剂盒) by introducing it into normal mouse pro-B cells; B-cell linker protein (Blnk) is repressed by PAX5 (显示 PAX5 ELISA试剂盒)-PML (显示 PML ELISA试剂盒) in leukemia cells; enforced expression of Blnk increases survival despite introduction of PAX5 (显示 PAX5 ELISA试剂盒)-PML (显示 PML ELISA试剂盒).

  3. B-cell linker protein expression contributes to controlling allergic and autoimmune diseases by mediating IL-10 (显示 IL10 ELISA试剂盒) production in regulatory B cells.

  4. Tumor suppressor BLNK is a target of transcriptional activation by PU.1 and Spi-B (显示 SPIB ELISA试剂盒) in the B cell lineage.

  5. a novel negative feedback regulation of BCR (显示 BCR ELISA试剂盒) signaling by HPK1-mediated phosphorylation, ubiquitination, and subsequent degradation of the activated BLNK

  6. CMTM7 (显示 CMTM7 ELISA试剂盒) functions to link sIgM and BLNK in the plasma membrane.

  7. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 and CIN85 (显示 SH3KBP1 ELISA试剂盒) are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  8. malignant transformation of Btk (显示 BTK ELISA试剂盒)/Slp65 double-deficient pre-B cells is independent of deregulated V(D)J recombination activity.

  9. Swip-1 (显示 WSB1 ELISA试剂盒) provides a membrane scaffold that is required for the Syk (显示 SYK ELISA试剂盒)-, SLP-65-, and PLCgamma2 (显示 PLCG2 ELISA试剂盒)-dependent BCR (显示 BCR ELISA试剂盒)-induced calcium flux.

  10. malignant transformation of Slp65(-/-) pre-B cells involves disruption of the p19(Arf)-Mdm2-p53 tumor suppressor pathway

Human B-Cell Linker (BLNK) interaction partners

  1. vesicular signaling scaffolds are required for B cell activation indicates that vesicles may deliver preassembled signaling cargo to sites of BCR (显示 BCR ELISA试剂盒) activation.

  2. early Ca(2 (显示 CA2 ELISA试剂盒)+) fluxing provides feed-forward signal amplification by promoting anchoring of the PLCgamma2 (显示 PLCG2 ELISA试剂盒) C2 domain to phospho-SLP65.

  3. up-regulation of BLNK is associated with RUNX1 (显示 RUNX1 ELISA试剂盒) mutations in cytogenetically normal acute myeloid leukemia (显示 BCL11A ELISA试剂盒).

  4. Live cell imaging and co-immunoprecipitation experiments confirmed that both SLP65 and CIN85 (显示 SH3KBP1 ELISA试剂盒) are both required for the onset and progression phases of B-cell antigen receptor signal transduction.

  5. 16 of the 34 childhood pre-B acute lymphoblastic leukaemia samples that were tested showed a complete loss or drastic reduction of SLP-65 expression

  6. The BLNK protein is present in the majority of mediastinal B cell lymphomas.

  7. In B cells SLP-65 exists in a 180 kDa complex as well as in monomeric form.

  8. V(H) gene rearrangement represents a frequent feature in B-lymphoid malignancy, which can be attributed to SLP65 deficiency in many cases.

  9. Syk (显示 SYK ELISA试剂盒) is required to link phosphorylated SLP-65 to Ca(2 (显示 CA2 ELISA试剂盒)+) mobilization.

  10. Plasmacytoid dendritic cells express a signalosome consisting of Lyn (显示 LYN ELISA试剂盒), Syk (显示 SYK ELISA试剂盒), Btk (显示 BTK ELISA试剂盒), Slp65 (Blnk) and PLCgamma2 (显示 PLCG2 ELISA试剂盒). Triggering CD303 leads to tyrosine phosphorylation of Syk (显示 SYK ELISA试剂盒), Slp65, PLCgamma2 (显示 PLCG2 ELISA试剂盒) & cytoskeletal proteins.

B-Cell Linker (BLNK) 抗原简介

Antigen Summary

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with B-Cell Linker (BLNK) ELISA试剂盒

  • B-cell linker (BLNK) 抗体
  • B-cell linker (blnk) 抗体
  • B cell linker (Blnk) 抗体
  • B-cell linker (Blnk) 抗体
  • AGM4 抗体
  • BASH 抗体
  • bca 抗体
  • blnk 抗体
  • BLNK-S 抗体
  • Ly-57 抗体
  • LY57 抗体
  • Lyw-57 抗体
  • MGC147045 抗体
  • SLP-65 抗体
  • SLP65 抗体

Protein level used designations for B-Cell Linker (BLNK) ELISA试剂盒

B-cell linker , B-cell linker protein , b-cell linker protein-like , B-cell adapter containing a SH2 domain protein , B-cell adapter containing a Src homology 2 domain protein , cytoplasmic adapter protein , lymphocyte antigen 57 , src homology 2 domain-containing leukocyte protein of 65 kDa , B cell adaptor containing SH2 domain , B cell linker protein , B-cell activation , Src homology 2 domain-containing leukocyte protein of 65 kDa , Src homology [SH2] domain-containing leukocyte protein of 65 kD , B cell linker protein BLNK , B-cell adapter SH2 domain-containing protein , SLP-65

GENE ID SPECIES
100070841 Equus caballus
405764 Danio rerio
450641 Pan troglodytes
548350 Xenopus (Silurana) tropicalis
704363 Macaca mulatta
100306798 Salmo salar
100456635 Pongo abelii
100481331 Ailuropoda melanoleuca
100593492 Nomascus leucogenys
17060 Mus musculus
29760 Homo sapiens
395733 Gallus gallus
499356 Rattus norvegicus
486814 Canis lupus familiaris
100152350 Sus scrofa
510393 Bos taurus
100712978 Cavia porcellus
101111241 Ovis aries
100354716 Oryctolagus cuniculus
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