BCL2-Associated Athanogene 3 (BAG3) ELISA试剂盒

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. 再加上,我们可以发BAG3 抗体 (130)BAG3 蛋白 (11)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
BAG3 9531 O95817
小鼠 BAG3 BAG3 29810 Q9JLV1
大鼠 BAG3 BAG3 293524  
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0.061 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13至16个工作日
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小鸡 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12至14个工作日
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37.5 pg/mL 62.5-4000 pg/mL   96 Tests Log in to see 12至14个工作日
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Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12至14个工作日
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0.061 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 8至12个工作日
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0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12至14个工作日
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引用最多的BAG3 ELISA试剂盒

  1. Human BAG3 ELISA Kit for Sandwich ELISA - ABIN418041 : Pacheco, Berra, Morais, Sciani, Branco, Bosch, Chudzinski-Tavassi: Dynein function and protein clearance changes in tumor cells induced by a Kunitz-type molecule, Amblyomin-X. in PLoS ONE 2014 (PubMed)

适于 BAG3 相互作用对的更多 ELISA 试剂盒

Zebrafish BCL2-Associated Athanogene 3 (BAG3) interaction partners

  1. This study therefore identifies both BAG3 reduction and autophagy promotion as potential therapies for FLNC (显示 FLNC ELISA试剂盒)(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  2. findings showed that the P209L mutation causes BAG3 to aggregate; proposed that the gradual loss of available BAG3(wt) and BAG3(P209L) proteins results in insufficiency leading to myofibrillar disintegration

Human BCL2-Associated Athanogene 3 (BAG3) interaction partners

  1. Familial suffering of Dilated cardiomyopathy and carrying a heterozygous large deletion in the BAG3 gene.This gene encodes BCL2-associated athanogene 3 protein.

  2. BAG3 mutations are associated with DCM phenotypes. BAG3 should be added to cardiomyopathy gene panels for screening of DCM patients, and patients previously considered gene elusive should undergo sequencing of the BAG3 gene.

  3. The spatial regulation of mTORC1 exerted by BAG3 apparently provides the basis for a simultaneous induction of autophagy and protein synthesis to maintain the proteome under mechanical strain.

  4. This study therefore identifies both BAG3 reduction and autophagy promotion as potential therapies for FLNC (显示 FLNC ELISA试剂盒)(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  5. variants in TNNT2 (显示 TNNT2 ELISA试剂盒) and BAG3 are associated with a high propensity to life-threatening cardiomyopathy presenting from childhood and young adulthood.

  6. It has been demonstrated that HSPB8 (显示 HSPB8 ELISA试剂盒)-BAG3-HSP70 (显示 HSP70 ELISA试剂盒) ensures the functionality of stress granules and restores proteostasis by targeting defective ribosomal products for degradation.

  7. The authors propose that the chaperone-mediated autophagy function of BAG3 represents a specific host defense strategy to counteract the function of VP40 in promoting efficient egress and spread of virus particles.

  8. BAG3 bound to Hsp70 (显示 HSP70 ELISA试剂盒) at the same time as Hsp22 (显示 HSPB8 ELISA试剂盒), Hsp27 (显示 HSPB1 ELISA试剂盒), or alphaB-crystallin (显示 CRYAB ELISA试剂盒), suggesting that it might physically bring the chaperone families together into a complex.

  9. These results suggest that Bag1 (显示 BAG1 ELISA试剂盒) and Bag3 control the stability of the Hsc70 (显示 HSPA8 ELISA试剂盒)-client complex using at least two distinct protein-protein contacts, providing a previously under-appreciated layer of molecular regulation in the human Hsc70 (显示 HSPA8 ELISA试剂盒) system.

  10. we report the first mammalian model of a single amino acid mutation of BAG3 (P209L) in exon 3 of Bag3 associated with the development of muscle disease with left ventricular dysfunction and heart failure

Mouse (Murine) BCL2-Associated Athanogene 3 (BAG3) interaction partners

  1. interaction between BAG3 and HSP70 (显示 HSP70 ELISA试剂盒) is essential for BAG3 to stabilize small heat shock proteins and maintain cardiomyocyte protein homeostasis

  2. The spatial regulation of mTORC1 exerted by BAG3 apparently provides the basis for a simultaneous induction of autophagy and protein synthesis to maintain the proteome under mechanical strain.

  3. Genetic variation in BAG3 plays an important role in the prevention of ischemic tissue necrosis.

  4. The aim of this study was to investigate the possible hemodynamic effects of BAG3 performing both in vitro and in vivo experiments.

  5. Our findings that BAG3 is localized at the sarcolemma and t-tubules while modulating myocyte contraction and action potential duration through specific interaction with the beta1-adrenergic receptor and L-type Ca(2 (显示 CA2 ELISA试剂盒)+) channel provide novel insight into the role of BAG3 in cardiomyopathies and increased arrhythmia risks in heart failure.

  6. molecular association of MyHC and BIS is necessary for MyHC stabilization in skeletal muscle.

  7. BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.

  8. Bis is upregulated in astrocytes after hypoxia-ischemia; hypoxia-ischemia induces progressive cell death in the hippocampi of bis-positive mice, while hippocampal neurons are less vulnerable to hypoxia-ischemia in mice that lack Bis.

  9. Deletion of the bis gene results in a marked increase in the production of corticosterone that is associated with thymic atrophy.

  10. BAG3 and Hsc70 (显示 HSPA8 ELISA试剂盒) interact with actin capping protein (显示 TMOD4 ELISA试剂盒) CapZ (显示 CAPZA1 ELISA试剂盒) to maintain myofibrillar integrity under mechanical stress.

BAG3 抗原简介

Antigen Summary

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Gene names and symbols associated with BAG3

  • BCL2 associated athanogene 3 L homeolog (bag3.L) 抗体
  • BCL2-associated athanogene 3 (bag3) 抗体
  • BCL2 associated athanogene 3 (BAG3) 抗体
  • BCL2 associated athanogene 3 (bag3) 抗体
  • BCL-2-associated athanogene 3 (BAG3) 抗体
  • BCL2-associated athanogene 3 (Bag3) 抗体
  • Bcl2-associated athanogene 3 (Bag3) 抗体
  • AA407278 抗体
  • ATBAG3 抗体
  • BAG-3 抗体
  • BAG3 抗体
  • bag3-A 抗体
  • BCL-2-associated athanogene 3 抗体
  • Bis 抗体
  • CAIR-1 抗体
  • MFM6 抗体
  • mg638 抗体
  • MGC53113 抗体
  • T28J14.160 抗体
  • T28J14_160 抗体
  • zgc:100859 抗体

Protein level used designations for BAG3

BCL2-associated athanogene 3 , BAG family molecular chaperone regulator 3 , BAG family molecular chaperone regulator 3-like , BCL2-binding athanogene 3 , bcl-2-binding protein Bis , docking protein CAIR-1 , BAG-3 , Bcl-2-binding protein Bis , Bcl-2-interacting death suppressor , bcl-2-associated athanogene 3

GENE ID SPECIES
379174 Xenopus laevis
445139 Danio rerio
450778 Pan troglodytes
714420 Macaca mulatta
100145358 Xenopus (Silurana) tropicalis
100228262 Taeniopygia guttata
100481230 Ailuropoda melanoleuca
830613 Arabidopsis thaliana
9531 Homo sapiens
29810 Mus musculus
293524 Rattus norvegicus
486916 Canis lupus familiaris
782633 Bos taurus
423931 Gallus gallus
100156989 Sus scrofa
100358030 Oryctolagus cuniculus
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