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ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) ELISA试剂盒

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 抗体 (252)ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 蛋白 (8)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795

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大鼠 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 13至17个工作日
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适于 ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 相互作用对的更多 ELISA 试剂盒

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (显示 ABCB4 ELISA试剂盒), Bcrp (显示 ABCG2 ELISA试剂盒) and Mrp1 (显示 ABCC1 ELISA试剂盒) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Study investigated the effect of MDR1, CYP2D6 (显示 CYP2D6 ELISA试剂盒) and CYP2C19 (显示 CYP2C19 ELISA试剂盒) gene polymorphisms on prophylactic therapy response in migraine patients, suggested that migraine patients who receive topiramate prophylactic treatment should be assessed for the presence of the MDR1 C3435T polymorphism

  2. The GG and TT genotypes in CYP3A5 (显示 CYP3A5 ELISA试剂盒)*3 and ABCB1 C3435T, respectively, were linked with higher TPC.

  3. The study revealed the correlation between ABCB1 DNA promoter methylation with rs1128503 and rs2032582 polymorphisms in malaria and was related to increased expression of ABCB1 protein levels in complicated malaria group when compared to uncomplicated malaria and control groups.

  4. findings suggest that Tetrandrine prevents paclitaxel-induced MDR by inhibiting Pgp (显示 PGPEP1 ELISA试剂盒) overexpression through a mechanism that may involve the inhibition of NF-kappaB (显示 NFKB1 ELISA试剂盒) signaling in osteosarcoma.

  5. Results find that ABCB1 is a target of miR (显示 MLXIP ELISA试剂盒)-9 and reverses the effect of miR (显示 MLXIP ELISA试剂盒)-9-mediated chemoresistance in K562 chronic myelogenous leukemia cells.

  6. findings suggest that osimertinib, a clinically-approved third-generation EGFR (显示 EGFR ELISA试剂盒) TKI, can reverse ABCB1-mediated MDR, which supports the combination therapy with osimertinib and ABCB1 substrates may potentially be a novel therapeutic stategy in ABCB1-positive drug resistant cancers.

  7. Subcellular distribution of P-gp (显示 ABCB4 ELISA试剂盒) and subsequent downregulation by pristimerin contribute to overcoming ABCB1-mediated chemotherapeutic drug resistance. Our findings suggested inducing the decrease of P-gp (显示 ABCB4 ELISA试剂盒) membrane protein could be a new promising alternative therapeutic strategy in ABCB1-mediated Multidrug resistance.

  8. Rack1 (显示 GNB2L1 ELISA试剂盒) regulated P-Glycoprotein activity, which was necessary for adriamycin-induced P-Glycoprotein - mediated phosphorylation of Anxa2 (显示 ANXA2 ELISA试剂盒) and Erk1/2 (显示 MAPK1/3 ELISA试剂盒).

  9. we found that the C3435T MDR1 polymorphism does not affect blood levels of cortisol or ACTH (显示 POMC ELISA试剂盒) in healthy Japanese males. The effect size at alpha = 0.05 and at power 0.80 in the present sample size was 0.176 Thus, the present study suggests that the C3435T MDR1 polymorphism does not have a great impact on blood levels of cortisol or ACTH (显示 POMC ELISA试剂盒).

  10. ABCB1 1236C/T variants might play a role in the risk of Parkinson's disease, whereas ABCB1 3435C/T polymorphisms might not contribute to susceptibility to disease (Meta-Analysis)

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Chrysosplenetin inhibited P-gp (显示 ABCB4 ELISA试剂盒) activity and reverse the up-regulated P-gp (显示 ABCB4 ELISA试剂盒) and MDR1 (显示 ABCB4 ELISA试剂盒) levels induced by artemisinin.

  2. Tamsulosin and tolterodine with P-gp (显示 ABCB4 ELISA试剂盒) gene expression and activity in an enantiomer-specific way.

  3. Pgp (显示 ABCB4 ELISA试剂盒)-coupled ATPase (显示 DNAH8 ELISA试剂盒) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  4. Data show that human transgenic mutant huntingtin (显示 HTT ELISA试剂盒) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (显示 ABCB4 ELISA试剂盒)) which suggests that MDR1 (显示 ABCB4 ELISA试剂盒) might be a potential therapeutic target for Huntington's disease.

  5. In vitro and in vivo downregulation of the ATP binding cassette transporter (显示 ABCC3 ELISA试剂盒) B1 by the HMG-CoA reductase (显示 HMGCR ELISA试剂盒) inhibitor simvastatin

  6. Efficient chemoprotection of CDD (显示 CDA ELISA试剂盒) and MDR1 (显示 ABCB4 ELISA试剂盒) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (显示 FOXC1 ELISA试剂盒)-C and anthracycline application

  7. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (显示 ABCB4 ELISA试剂盒) substrates.

  8. Data indicate that the brain penetration of ABT-888 in both Abcb1a (显示 ABCB4 ELISA试剂盒)/1b-/- and Abcb1a (显示 ABCB4 ELISA试剂盒)/1b-/-;Abcg2 (显示 ABCG2 ELISA试剂盒)-/- mice was significantly higher than in wild-type mice.

  9. Expression of Abcb1 at the blood-brain and blood-spinal barriers is upregulated by Nrf2 (显示 NFE2L2 ELISA试剂盒).

  10. The improved structures of Pgp reveal important implications for polyspecific drug recognition in the form of a high concentration of aromatic residues in the drug translocation pathway that is most conserved among mammalian orthologs.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) 抗原简介

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 抗体
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) 抗体
  • malic enzyme complex, mitochondrial (Mod2) 抗体
  • ABC20 抗体
  • ABCB1 抗体
  • Cd243 抗体
  • CLCS 抗体
  • GP170 抗体
  • Mdr 抗体
  • Mdr-1 抗体
  • Mdr1 抗体
  • Mdr1a 抗体
  • Mdr1b 抗体
  • Mod-2 抗体
  • Mod-2r 抗体
  • Mod-2s 抗体
  • Mod2-r 抗体
  • Mod2-s 抗体
  • p-gp 抗体
  • PGP1 抗体
  • Pgy-1 抗体
  • Pgy1 抗体
  • xemdr 抗体

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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