ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) ELISA试剂盒

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 抗体 (280)ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 蛋白 (7)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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适于 ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 相互作用对的更多 ELISA 试剂盒

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (显示 ABCB4 ELISA试剂盒), Bcrp (显示 ABCG2 ELISA试剂盒) and Mrp1 (显示 ABCC1 ELISA试剂盒) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Results show that CD133 and MDR1 expression increase in recurrent pediatric pilocytic astrocytomas (PAs (显示 PASK ELISA试剂盒)) following chemotherapy, and in drug resistant tumor cells. CD133 regulates MDR1 expression via the PI3K (显示 PIK3CA ELISA试剂盒)/AKT (显示 AKT1 ELISA试剂盒)/NF-kappaB (显示 NFKB1 ELISA试剂盒) signaling. These results provide evidence that CD133 contributes to multidrug resistance by regulating MDR1 levels via the PI3K (显示 PIK3CA ELISA试剂盒)-Akt (显示 AKT1 ELISA试剂盒)-NF-kappaB (显示 NFKB1 ELISA试剂盒) signal pathway.

  2. PG accumulation assay is a new, unique tool for the parallel determination of the function of the ABCG2 (显示 ABCG2 ELISA试剂盒), ABCB1, and ABCC1 (显示 ABCC1 ELISA试剂盒) multidrug transporters

  3. Abcb1a/b(-/-);Abcg2 (显示 ABCG2 ELISA试剂盒)(-/-) mice revealed increased brain penetration of rapamycin (13-fold), AZD8055 (7.7-fold), and NVP-BEZ235 (4.5-fold), but not ZSTK474 relative to WT mice. Importantly, ABC (显示 ABCB6 ELISA试剂盒) transporters limited rapamycin brain penetration to subtherapeutic levels, while the reduction in NVP-BEZ235 brain penetration did not prevent target inhibition.

  4. ABCB1 genotype is not a significant determinant of interindividual variability in dabigatran and rivaroxaban pharmacokinetics

  5. High MDR1 expression is associated with multidrug resistance in breast cancer.

  6. inhibition of autophagy led to the decrease in stemness, restoration of mitochondrial proteins and reduced expression of CD44 (显示 CD44 ELISA试剂盒), ABCB1 and ADAM17 (显示 ADAM17 ELISA试剂盒)

  7. The T-allele of ABCB1-C3435T gene polymorphism has demonstrated to be a good prognosis factor for resistance, progression free survival and overall survival in HER2 (显示 ERBB2 ELISA试剂盒)-positive Breast Cancer patients.

  8. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (显示 ABCB4 ELISA试剂盒)--{REVIEW}

  9. Studied ABCB1 protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1-expressing neurons in the left habenula.

  10. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (显示 ABCC6 ELISA试剂盒), ABCB1 and CYP2C8 (显示 CYP2C8 ELISA试剂盒) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp (显示 ABCB4 ELISA试剂盒), multi-drug resistance protein, MDR1 (显示 ABCB4 ELISA试剂盒)).Drugs with ER < 1 (显示 MIER1 ELISA试剂盒) almost do not bind the main binding cavity (MBC (显示 CACNA1C ELISA试剂盒)) of P-gp (显示 ABCB4 ELISA试剂盒).

  2. conclusion, MDR1 (显示 ABCB4 ELISA试剂盒) and BCRP (显示 ABCG2 ELISA试剂盒) are expressed on apical membranes of the rodent placental SynT (显示 STX1A ELISA试剂盒)-II layer.

  3. Mdr1 (显示 ABCB4 ELISA试剂盒) enforces T Cell homeostasis in the presence of intestinal bile acids.

  4. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  5. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (显示 ABCB4 ELISA试剂盒) ATPase (显示 DNAH8 ELISA试剂盒) activity

  6. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  7. Chrysosplenetin inhibited P-gp (显示 ABCB4 ELISA试剂盒) activity and reverse the up-regulated P-gp (显示 ABCB4 ELISA试剂盒) and MDR1 (显示 ABCB4 ELISA试剂盒) levels induced by artemisinin.

  8. Tamsulosin and tolterodine with P-gp (显示 ABCB4 ELISA试剂盒) gene expression and activity in an enantiomer-specific way.

  9. Pgp (显示 ABCB4 ELISA试剂盒)-coupled ATPase (显示 DNAH8 ELISA试剂盒) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  10. Data show that human transgenic mutant huntingtin (显示 HTT ELISA试剂盒) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (显示 ABCB4 ELISA试剂盒)) which suggests that MDR1 (显示 ABCB4 ELISA试剂盒) might be a potential therapeutic target for Huntington's disease.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) 抗原简介

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP binding cassette subfamily B member 1 (ABCB1) 抗体
  • ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) 抗体
  • ATP binding cassette subfamily B member 1A (Abcb1a) 抗体
  • ATP binding cassette subfamily B member 1 (Abcb1) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) 抗体
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) 抗体
  • malic enzyme complex, mitochondrial (Mod2) 抗体
  • ABC20 抗体
  • ABCB1 抗体
  • Cd243 抗体
  • CLCS 抗体
  • GP170 抗体
  • Mdr 抗体
  • Mdr-1 抗体
  • Mdr1 抗体
  • Mdr1a 抗体
  • Mdr1b 抗体
  • Mod-2 抗体
  • Mod-2r 抗体
  • Mod-2s 抗体
  • Mod2-r 抗体
  • Mod2-s 抗体
  • p-gp 抗体
  • PGP1 抗体
  • Pgy-1 抗体
  • Pgy1 抗体
  • xemdr 抗体

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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