This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons. [provided by RefSeq, Feb 2012].
zinc and ring finger 1 (ZNRF1) 蛋白 zinc and ring finger 1 (Znrf1) 蛋白 zinc and ring finger 1 (znrf1) 蛋白 zinc and ring finger 1, E3 ubiquitin protein ligase S homeolog (znrf1.S) 蛋白 B830022L21Rik 蛋白 NIN283 蛋白 nin283 蛋白 Rnf42 蛋白 zgc:77896 蛋白 Zrfp1 蛋白 zrfp1 蛋白