This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons. [provided by RefSeq, Feb 2012].
Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).
Aliases for ZNRF1 抗体
zinc and ring finger 1 (ZNRF1) 抗体 zinc and ring finger 1 (Znrf1) 抗体 zinc and ring finger 1 (znrf1) 抗体 zinc and ring finger 1, E3 ubiquitin protein ligase S homeolog (znrf1.S) 抗体 B830022L21Rik 抗体 NIN283 抗体 nin283 抗体 Rnf42 抗体 zgc:77896 抗体 Zrfp1 抗体 zrfp1 抗体