This gene encodes a member of the zinc finger domain-containing protein family. This family member contains both a RING-type and a C2H2-type of zinc finger domain, and it may function as an E3 ubiquitin-protein ligase. Protein localization suggests a role in human sperm production and quality control. [provided by RefSeq, Aug 2011].
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Liu, Bai, Zhang, Su, Tao, Yang, Ma, Zhang: "Human RING finger protein ZNF645 is a novel testis-specific E3 ubiquitin ligase." in: Asian journal of andrology, Vol. 12, Issue 5, pp. 658-66, (2010) (PubMed).