Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat- induced viral LTR promoter activity.
Carlson, Limoges, Pohlman, Poluektova, Langford, Masliah, Ikezu, Gendelman: "OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis." in: Journal of neuroimmunology, Vol. 150, Issue 1-2, pp. 186-98, (2004) (PubMed).
Grimwood, Gordon, Olsen, Terry, Schmutz, Lamerdin, Hellsten, Goodstein, Couronne, Tran-Gyamfi, Aerts, Altherr, Ashworth, Bajorek, Black, Branscomb, Caenepeel, Carrano, Caoile, Chan, Christensen et al.: "The DNA sequence and biology of human chromosome 19. ..." in: Nature, Vol. 428, Issue 6982, pp. 529-35, (2004) (PubMed).
Carlson, Leisman, Limoges, Pohlman, Horiba, Buescher, Gendelman, Ikezu: "Molecular characterization of a putative antiretroviral transcriptional factor, OTK18." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 1, pp. 381-91, (2003) (PubMed).
Saito, Fujiwara, Takahashi, Shin, Okui, Nakamura: "Isolation and mapping of a novel human gene encoding a protein containing zinc-finger structures." in: Genomics, Vol. 31, Issue 3, pp. 376-9, (1997) (PubMed).
Aliases for ZNF175 抗体
zinc finger protein 175 (ZNF175) 抗体 OTK18 抗体 ZNF175 抗体