This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.[provided by RefSeq, May 2010].
Mukai, Liu, Burt, Swor, Lai, Karayiorgou, Gogos: "Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia." in: Nature genetics, Vol. 36, Issue 7, pp. 725-31, (2004) (PubMed).