ZC3HC1 蛋白
(Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry (By similarity).
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3 results
Aliases for ZC3HC1 蛋白
zinc finger, C3HC type 1 (Zc3hc1) 蛋白zinc finger C3HC-type containing 1 (ZC3HC1) 蛋白
zinc finger, C3HC-type containing 1 (Zc3hc1) 蛋白
1110054L24Rik 蛋白
AU018540 蛋白
AU019789 蛋白
HSPC216 蛋白
Nipa 蛋白
NIPA 蛋白
RGD1561099 蛋白
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