(Zinc Finger and BTB Domain Containing 38 (ZBTB38))
The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types. [provided by RefSeq, Jun 2010].
Sasai, Matsuda, Sarashina, Ishida, Kawaichi: "Identification of a novel BTB-zinc finger transcriptional repressor, CIBZ, that interacts with CtBP corepressor." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 10, Issue 9, pp. 871-85, (2005) (PubMed).
Kiefer, Chatail-Hermitte, Ravassard, Bayard, Brunet, Mallet: "ZENON, a novel POZ Kruppel-like DNA binding protein associated with differentiation and/or survival of late postmitotic neurons." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1713-29, (2005) (PubMed).
Melnick, Carlile, Ahmad, Kiang, Corcoran, Bardwell, Prive, Licht: "Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors." in: Molecular and cellular biology, Vol. 22, Issue 6, pp. 1804-18, (2002) (PubMed).
Deltour, Pinte, Guerardel, Wasylyk, Leprince: "The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif." in: Molecular and cellular biology, Vol. 22, Issue 13, pp. 4890-901, (2002) (PubMed).
Zhang, Chen, Chen, Yu, Li, Lv, Wang, Li, Li, Cai: "Tauroursodeoxycholic acid alleviates secondary injury in the spinal cord via up-regulation of CIBZ gene." in: Cell stress & chaperones (PubMed).