(Zinc Finger and BTB Domain Containing 32 (ZBTB32))
DNA-binding protein that binds to the to a 5'- TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor (By similarity). Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.
Hoatlin, Zhi, Ball, Silvey, Melnick, Stone, Arai, Hawe, Owen, Zelent, Licht: "A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF." in: Blood, Vol. 94, Issue 11, pp. 3737-47, (1999) (PubMed).