XRCC5 产品
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
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The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008].
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Featured XRCC5 Categories
XRCC5 抗体
High quality antibodies with extensive validation data.
XRCC5 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
XRCC5 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended XRCC5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (3)
- (6)
Cat. No.
ABIN563391
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (2)
- (12)
Cat. No.
ABIN6150309
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7010873
Quantity
60 μL
Datasheet
Datasheet
Recommended XRCC5 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971209
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960572
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960573
Quantity
96 tests
Datasheet
Datasheet
Recommended XRCC5 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325473
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3096359
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5710636
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our XRCC5 Products
: "Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 20, Issue 12, pp. 3679-3687, (2020) (PubMed).: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).
: "BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy." in: Cancer letters, Vol. 423, pp. 60-70, (2018) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "Influence of XRCC4 expression in esophageal cancer cells on the response to radiotherapy." in: Medical molecular morphology, Vol. 50, Issue 1, pp. 25-33, (2016) (PubMed).
: "Expression of Ku70 predicts results of radiotherapy in prostate cancer." in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], Vol. 193, Issue 1, pp. 29-37, (2016) (PubMed).
: "Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs." in: Cancer research, Vol. 73, Issue 2, pp. 1000-10, (2013) (PubMed).
: "Serum anti-Ku86 is a potential biomarker for early detection of hepatitis C virus-related hepatocellular carcinoma." in: Biochemical and biophysical research communications, Vol. 421, Issue 4, pp. 837-43, (2012) (PubMed).
: "Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines." in: Breast cancer research : BCR, Vol. 11, Issue 6, pp. R83, (2010) (PubMed).
: "The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A." in: BMC medicine, Vol. 8, pp. 19, (2010) (PubMed).
Synonyms and alternative names related to XRCC5
X-ray repair cross complementing 5 (XRCC5), X-ray repair complementing defective repair in Chinese hamster cells 5 (Xrcc5), X-ray repair cross complementing 5 (Xrcc5), X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog (xrcc5.L), AI314015, KARP-1, KARP1, Ku80, KU80, Ku86, KUB2, Kup80, NFIV, XRCC5, xrcc5-aProtein level used designations for XRCC5
- Ku autoantigen
- X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)
- X-ray repair protein
- X-ray repair cross-complementing protein 5
- X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- ATP-dependent DNA helicase II
- ATP-dependent DNA helicase 2 subunit 2-like
- x-ray repair cross-complementing protein 5-like
- ATP-dependent DNA helicase 2 subunit 2
- ATP-dependent DNA helicase II 80 kDa subunit
- CTC box-binding factor 85 kDa subunit
- CTC85
- CTCBF
- DNA repair protein XRCC5
- Ku p80
- ku autoantigen protein p86 homolog
- nuclear factor IV
- Ku autoantigen, 80kD)
- X-ray repair cross complementation (double-strand-break rejoining
- X-ray repair cross complementation (double-strand-break rejoining; Ku autoantigen, 80kD)
- 86 kDa subunit of Ku antigen
- Ku autoantigen, 80kDa
- Ku86 autoantigen related protein 1
- TLAA
- lupus Ku autoantigen protein p86
- thyroid-lupus autoantigen
- X-ray repair complementing defective repair in Chinese hamster cells 5
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