XRCC4 蛋白
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008].
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9 results
XRCC4
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
ELISA, WB
custom-made
XRCC4
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Latest Publications for our XRCC4 蛋白
: "Quantification of XRCC and DNA-PK proteins in cancer cell lines and human tumors by LC-MS/MS." in: Bioanalysis, Vol. 6, Issue 22, pp. 2969-83, (2014) (PubMed).
Aliases for XRCC4 蛋白
X-ray repair cross complementing 4 (XRCC4) 蛋白X-ray repair complementing defective repair in Chinese hamster cells 4 (xrcc4) 蛋白
X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog (xrcc4.L) 蛋白
DNA ligase IV-binding protein (XRCC4) 蛋白
X-ray repair complementing defective repair in Chinese hamster cells 4 (Xrcc4) 蛋白
X-ray repair cross complementing 4 (Xrcc4) 蛋白
2310057B22Rik 蛋白
AW413319 蛋白
AW545101 蛋白
homolog of human DNA ligase iv-binding protein XRCC4 蛋白
MGC81443 蛋白
zgc:73312 蛋白
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