WWP1 蛋白
(WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1\; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| WWP1 Protein (AA 1-233) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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|
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| WWP1 Protein (GST tag) | 人 | Baculovirus infected Insect Cells |
|
|
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| WWP1 Protein (AA 1-922) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
|
|
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| WWP1 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
|
|
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| WWP1 Protein (AA 17-141) (His tag) | 人 | Bacteria |
|
|
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Aliases for WWP1 蛋白
WW domain containing E3 ubiquitin protein ligase 1 (WWP1) 蛋白WW domain containing E3 ubiquitin protein ligase 1 (Wwp1) 蛋白
WW domain containing E3 ubiquitin protein ligase 1 (wwp1) 蛋白
8030445B08Rik 蛋白
AIP5 蛋白
aip5 蛋白
hSDRP1 蛋白
hsdrp1 蛋白
SDRP1 蛋白
Tiul1 蛋白
tiul1 蛋白
WWP1 蛋白
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