WHSC1 抗体
(Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4\;14)(p16.3\;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008].
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Latest Publications for our WHSC1 抗体
: "The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies. ..." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 25, Issue 1, pp. 300-311, (2019) (PubMed).: "MMSET is dynamically regulated during cell-cycle progression and promotes normal DNA replication." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 1, pp. 95-105, (2016) (PubMed).
: "NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation." in: Scientific reports, Vol. 6, pp. 32952, (2016) (PubMed).
: "NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma." in: Cancer research, Vol. 73, Issue 20, pp. 6277-88, (2013) (PubMed).
: "Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway." in: Neoplasia (New York, N.Y.), Vol. 13, Issue 10, pp. 887-98, (2011) (PubMed).
: "The protein expression of TRP-1 and galectin-1 in cutaneous malignant melanomas." in: Cancer genomics & proteomics, Vol. 5, Issue 6, pp. 293-300, (2009) (PubMed).
: "Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas." in: Neuro-oncology, Vol. 10, Issue 1, pp. 45-51, (2008) (PubMed).
: "The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor." in: Blood, Vol. 111, Issue 6, pp. 3145-54, (2008) (PubMed).
Aliases for WHSC1 抗体
nuclear receptor binding SET domain protein 2 (NSD2) 抗体nuclear receptor binding SET domain protein 2 (nsd2) 抗体
Wolf-Hirschhorn syndrome candidate 1 (WHSC1) 抗体
nuclear receptor binding SET domain protein 2 (Nsd2) 抗体
5830445G22Rik 抗体
9430010A17Rik 抗体
AW555663 抗体
C130020C13Rik 抗体
D030027O06Rik 抗体
D930023B08Rik 抗体
fc12c04 抗体
mKIAA1090 抗体
mmset 抗体
MMSET 抗体
nsd2 抗体
NSD2 抗体
reiibp 抗体
REIIBP 抗体
RGD1565590 抗体
si:rp71-77d7.2 抗体
trx5 抗体
TRX5 抗体
whs 抗体
WHS 抗体
WHSC1 抗体
Whsc1l 抗体
wu:fc12c04 抗体
wu:fi20c01 抗体
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