The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined. [provided by RefSeq, Jul 2008].
Chan, Lim, Huang, Chong, Gunaratne, Hogue, Blackstock, Harvey, Hong: "WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ." in: Oncogene, Vol. 30, Issue 5, pp. 600-10, (2011) (PubMed).
Lim, Orhant-Prioux, Toy, Tan, Lim: "Tyrosine phosphorylation of transcriptional coactivator WW-domain binding protein 2 regulates estrogen receptor ? function in breast cancer via the Wnt pathway." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 9, pp. 3004-18, (2011) (PubMed).
Aliases for WBP2 抗体
WW domain binding protein 2 (WBP2) 抗体 WW domain binding protein 2 (Wbp2) 抗体 WW domain binding protein 2 L homeolog (wbp2.L) 抗体 WW domain binding protein 2 (wbp2) 抗体 MGC68743 抗体 WBP-2 抗体 wbp-2 抗体 zgc:109985 抗体