WASF1 蛋白
(WAS Protein Family, Member 1 (WASF1))
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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WASF1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for WASF1 蛋白
WAS protein family member 1 S homeolog (wasf1.S) 蛋白SCAR family protein (AT2G34150) 蛋白
WAS protein family member 1 (wasf1) 蛋白
WAS protein family member 1 (WASF1) 蛋白
WAS protein family, member 1 (Wasf1) 蛋白
AI195380 蛋白
AI838537 蛋白
ATRANGAP2 蛋白
ATSCAR1 蛋白
Scar 蛋白
scar1 蛋白
SCAR1 蛋白
T14G11.27 蛋白
T14G11_27 蛋白
wave 蛋白
WAVE 蛋白
WAVE-1 蛋白
wave1 蛋白
WAVE1 蛋白
WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 1 蛋白
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