WASF1 抗体
(WAS Protein Family, Member 1 (WASF1))
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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Latest Publications for our WASF1 抗体
: "Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion." in: The EMBO journal, Vol. 33, Issue 23, pp. 2745-64, (2014) (PubMed).: "The WAVE regulatory complex links diverse receptors to the actin cytoskeleton." in: Cell, Vol. 156, Issue 1-2, pp. 195-207, (2014) (PubMed).
: "Local F-actin network links synapse formation and axon branching." in: Cell, Vol. 156, Issue 1-2, pp. 208-20, (2014) (PubMed).
: "SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties." in: Nature, Vol. 503, Issue 7474, pp. 72-7, (2013) (PubMed).
: "Major signaling pathways in migrating neuroblasts." in: Frontiers in molecular neuroscience, Vol. 2, pp. 7, (2009) (PubMed).
: "WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2." in: Nature cell biology, Vol. 10, Issue 7, pp. 849-57, (2008) (PubMed).
: "Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 7, pp. 1519-28, (2007) (PubMed).
: "Src-dependent phosphorylation of Scar1 promotes its association with the Arp2/3 complex." in: Cell motility and the cytoskeleton, Vol. 63, Issue 1, pp. 6-13, (2006) (PubMed).
: "Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 4, pp. 1098-103, (2005) (PubMed).
: "Crystal growth of carbonate apatite using a CaCO3 flux." in: Journal of materials science. Materials in medicine, Vol. 10, Issue 9, pp. 561-6, (2004) (PubMed).
Aliases for WASF1 抗体
WAS protein family member 1 S homeolog (wasf1.S) 抗体SCAR family protein (AT2G34150) 抗体
WAS protein family member 1 (wasf1) 抗体
WAS protein family member 1 (WASF1) 抗体
WAS protein family, member 1 (Wasf1) 抗体
AI195380 抗体
AI838537 抗体
ATRANGAP2 抗体
ATSCAR1 抗体
Scar 抗体
scar1 抗体
SCAR1 抗体
T14G11.27 抗体
T14G11_27 抗体
wave 抗体
WAVE 抗体
WAVE-1 抗体
wave1 抗体
WAVE1 抗体
WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 1 抗体
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