Component of the Cul4a-Rbx1-Ddb1-Vprbp/Dcaf1 E3 ubiquitin-protein ligase complex, Vprbp/Dcaf1 may function as the substrate recognition module within this complex (By similarity). Associated with chromatin in a Ddb1-independent and cell cycle- dependent manner, Vprbp/Dcaf1 is recruited to chromatin as DNA is being replicated and is released from chromatin before mitosis (By similarity).
Britschgi, Duss, Kim, Couto, Brinkhaus, Koren, De Silva, Mertz, Kaup, Varga, Voshol, Vissieres, Leroy, Roloff, Stadler, Scheel, Miraglia, Orth, Bonamy, Reddy, Bentires-Alj: "The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα." in: Nature, Vol. 541, Issue 7638, pp. 541-545, (2017) (PubMed).
Salsman, Jagannathan, Paladino, Chan, Dellaire, Raught, Frappier: "Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response." in: Journal of virology, Vol. 86, Issue 2, pp. 806-20, (2011) (PubMed).
Aliases for VPRBP 抗体
DDB1 and CUL4 associated factor 1 (Dcaf1) 抗体 DDB1 and CUL4 associated factor 1 (DCAF1) 抗体 protein VPRBP (LOC100175926) 抗体 Vpr (HIV-1) binding protein (vprbp) 抗体 DDB1 and CUL4 associated factor 1 (dcaf1) 抗体 AI447437 抗体 B930007L02Rik 抗体 DCAF1 抗体 mKIAA0800 抗体 RGD1305176 抗体