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VAV1 蛋白

(Vav 1 Oncogene (VAV1))
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012].

10 results :

custom-made VAV1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7545081
 
VAV1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
产品编号 ABIN7125706
 
VAV1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1324929
 
VAV1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pubmed 1 reference
产品编号 ABIN2735197
 
VAV1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7580213
 
VAV1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7418038
 
VAV1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC
产品编号 ABIN7417078
 
VAV1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % pure SDS
产品编号 ABIN2132495
 
custom-made VAV1 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
产品编号 ABIN3075384
 
Rockland 009-001-u55s VAV1 宿主: 人 宿主: Insect cells (Sf9) Recombinant >70% WB
产品编号 ABIN6700863
Rockland Original
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Insect cells (Sf9)
    • Wheat germ
  • 抗原表位
    • AA 1-845
    • AA 189-565
    • AA 426-696
    • AA 565-795
    • AA 681-790
  • 标记
    • GST tag
    • His tag
    • His tag,GST tag
    • Myc-DYKDDDDK Tag
    • Strep Tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene
    • Rockland

Latest Publications for our VAV1 蛋白

Mahankali, Peng, Henkels, Dinauer, Gomez-Cambronero: "Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 49, pp. 19617-22, (2011) (PubMed).

Aliases for VAV1 蛋白

vav guanine nucleotide exchange factor 1 (VAV1) 蛋白
vav guanine nucleotide exchange factor 1 (Vav1) 蛋白
vav 1 oncogene (Vav1) 蛋白
vav guanine nucleotide exchange factor 1 L homeolog (vav1.L) 蛋白
VAV 蛋白
Vav 蛋白
vav-T 蛋白
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