USP15 抗体
(Ubiquitin Specific Peptidase 15 (USP15))
This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011].
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Latest Publications for our USP15 抗体
: "Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity." in: Oncotarget, Vol. 8, Issue 66, pp. 110490-110502, (2018) (PubMed).: "Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms." in: Scientific reports, Vol. 5, pp. 11220, (2016) (PubMed).
: "The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25." in: Science signaling, Vol. 7, Issue 307, pp. ra3, (2014) (PubMed).
: "The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity." in: Neuron, Vol. 83, Issue 5, pp. 1144-58, (2014) (PubMed).
: "The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy." in: Human molecular genetics, Vol. 23, Issue 19, pp. 5227-42, (2014) (PubMed).
: "OTUB1 modulates c-IAP1 stability to regulate signalling pathways." in: The EMBO journal, Vol. 32, Issue 8, pp. 1103-14, (2013) (PubMed).
: "Transgenic overexpression of USP15 in the heart induces cardiac remodeling in mice." in: Biochemical and biophysical research communications, Vol. 405, Issue 2, pp. 216-21, (2011) (PubMed).
: "The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17390-7, (2010) (PubMed).
: "The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability." in: Journal of virology, Vol. 83, Issue 17, pp. 8885-92, (2009) (PubMed).
: "USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis." in: Biochemical and biophysical research communications, Vol. 388, Issue 2, pp. 366-71, (2009) (PubMed).
Aliases for USP15 抗体
ubiquitin specific peptidase 15 (USP15) 抗体universal stress protein UspA (RR_RS05795) 抗体
ubiquitin carboxyl-terminal hydrolase 15 (LOC100090554) 抗体
ubiquitin specific peptidase 15 (usp15) 抗体
ubiquitin specific peptidase 15 (Usp15) 抗体
4921514G19Rik 抗体
AI327321 抗体
E430033I05Rik 抗体
Gcap18 抗体
mKIAA0529 抗体
Ubp109 抗体
UNP 抗体
UNPH-2 抗体
UNPH4 抗体
USP15 抗体
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