ULBP1 抗体
(UL16 Binding Protein 1 (ULBP1))
Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis- Golgi apparatus so that it does not reach the cell surface.
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27 results
Latest Publications for our ULBP1 抗体
: "Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer." in: Cancer research, Vol. 80, Issue 23, pp. 5355-5366, (2021) (PubMed).: "Effects of obesity on NK cells in a mouse model of postmenopausal breast cancer." in: Scientific reports, Vol. 10, Issue 1, pp. 20606, (2020) (PubMed).
: "Expression of ligands for activating natural killer cell receptors on cell lines commonly used to assess natural killer cell function." in: BMC immunology, Vol. 20, Issue 1, pp. 8, (2019) (PubMed).
: "NKG2D Regulation of Lung Pathology and Dendritic Cell Function Following Respiratory Syncytial Virus Infection." in: The Journal of infectious diseases, Vol. 218, Issue 11, pp. 1822-1832, (2019) (PubMed).
: "The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy." in: Cell death & disease, Vol. 10, Issue 10, pp. 695, (2019) (PubMed).
: "Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model." in: Scientific reports, Vol. 9, Issue 1, pp. 10840, (2019) (PubMed).
: "Control of triple-negative breast cancer using ex vivo self-enriched, costimulated NKG2D CAR T cells." in: Journal of hematology & oncology, Vol. 11, Issue 1, pp. 92, (2018) (PubMed).
: "Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 8, pp. 1834-1844, (2018) (PubMed).
: "Immunotherapy of Dual-Function Vector with Both Immunostimulatory and B-Cell Lymphoma 2 (Bcl-2)-Silencing Effects on Gastric Carcinoma." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 1980-1991, (2017) (PubMed).
: "Expression Profiles of Ligands for Activating Natural Killer Cell Receptors on HIV Infected and Uninfected CD4⁺ T Cells." in: Viruses, Vol. 9, Issue 10, (2017) (PubMed).
Aliases for ULBP1 抗体
UL16 binding protein 1 (ULBP1) 抗体UL16 binding protein 21 (ULBP21) 抗体
UL16 binding protein 1 (Ulbp1) 抗体
NKG2D ligand 1 (LOC100683099) 抗体
A430108B07Rik 抗体
MULT1 抗体
RAET1I 抗体
ULBP1 抗体
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