UBP1 抗体

Functions as a transcriptional activator in a promoter context-dependent manner. Involved in regulation of the alpha- globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Functions as a trans-acting factor that regulates the domestic strain CYP2D9 gene through specific association with the regulatory element SDI-A1. Binding to SDI-A1 depends on the type of nucleotide at position 299\; binding is abolished by a nucleotide substitution at this position. Modulates the placental expression of CYP11A1 (By similarity).