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抗Human IRX1 抗体:
抗Mouse (Murine) IRX1 抗体:
抗Rat (Rattus) IRX1 抗体:
Human Polyclonal IRX1 Primary Antibody for ELISA, WB - ABIN566348
Zougman, Mann, Wisniewski: Identification and characterization of a novel ubiquitous nucleolar protein 'NARR' encoded by a gene overlapping the rab34 oncogene. in Nucleic acids research 2011
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A total of three nonsynonymous mutations (p.Gln240Glu, p.Ser298Asn and p.Ala381Glu) of the IRX1 (显示 IRX3 抗体) gene were verified in 215 nonsyndromic congenital heart disease patients.
this is the first genome-wide association study of Rheumatoid Factor positivity in Rheumatoid Arthritis. Variation at the IRX1 (显示 IRX3 抗体) locus on chromosome 5p15.3 is associated with the presence of Rheumatoid Factor. Our findings indicate that IRX1 (显示 IRX3 抗体) and HLA-DRB1 (显示 HLA-DRB1 抗体) are the strongest genetic factors for Rheumatoid Factor production in Rheumatoid Arthritis.
In osteosarcoma cells and lines, IRX1 (显示 IRX3 抗体) overexpression was associated with hypomethylation of its own promoter. Experimental modulation in cell lines altered migration, invasion, and resistance to anoikis in vitro, and influenced lung metastasis in mice.
Findings suggest that methylation-associated down-regulation of EBF3 (显示 MAPRE3 抗体) and IRX1 (显示 IRX3 抗体) genes may play an important role in a pathogenic effect of TGF-beta (显示 TGFB1 抗体) on RASFs.
Helicobacter pylori infection contributes to IRX1 (显示 IRX3 抗体) promoter methylation in gastric mucosa.
enforcing IRX1 (显示 IRX3 抗体) expression effectively suppresses peritoneal spreading and pulmonary metastasis via anti-angiogenesis and anti-VM mechanisms, in addition to previously found cell growth and invasion.
Homeobox (显示 Lbx1 抗体) gene IRX1 (显示 IRX3 抗体) is a tumor suppressor gene in gastric carcinoma.
Results verify IRX1 (显示 IRX3 抗体), EBF3 (显示 MAPRE3 抗体), SLC5A8 (显示 SLC5A8 抗体), SEPT9 (显示 SEPT9 抗体), and FUSSEL18 (显示 SKOR2 抗体) as valid methylation markers in two separate sets of HNSCC specimens; also preliminarily show a trend between HPV16 positivity and target gene hypermethylation of IRX1 (显示 IRX3 抗体), EBF3 (显示 MAPRE3 抗体), SLC5A8 (显示 SLC5A8 抗体), and SEPT9 (显示 SEPT9 抗体).
Frequent methylation of IRX1 (显示 IRX3 抗体) gene is associated with head and neck squamous cell carcinoma
Irx1 regulates Foxj1 (显示 FOXJ1 抗体) and Sox9 (显示 SOX9 抗体) to control cell differentiation during development.
This homeobox protein (显示 HOXA1 抗体) is expressed during early lung development.
This homeobox protein (显示 HOXA1 抗体) is expressed during digit development and is an early marker for this development.
Observations suggest that Irx2 (显示 IRX2 抗体) functions downstream of irx1a to control shh (显示 SHH 抗体) expression in the retina. Study proposed a novel transcriptional cascade of ath5 (显示 ATOH7 抗体)-irx1a-irx2a in the regulation of hedgehog (显示 SHH 抗体) waves during vertebrate retinal development.
Data revealed that expression of DNA binding inhibitor 3 (显示 PPP1R11 抗体), early B cell factor 2 (显示 EBF2 抗体), Ebf3 (显示 EBF3 抗体), Iroquois related homeobox 1, Kruppel-like factor 7 , mab-21-like 1 (显示 MAB21L1 抗体) , fatty acid binding protein 7 (显示 FABP7 抗体) and stathmin-like 4 (显示 STMN4 抗体),were enriched in the diencephalon of zebrafish.
Our results reveal a role for Iroquois genes in controlling hedgehog (显示 SHH 抗体) expression during vertebrate retinogenesis.
irx1a is not required for the initial specification but it is required for the complete differentiation of 5HT (显示 DDC 抗体) neurons
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13.
homeodomain protein IRXA1
, iroquois homeobox protein 1
, iroquois-class homeodomain protein IRX-1
, iroquois homologue-1
, iroquois homeobox 1
, iroquois-class homeodomain protein irx-1
, Iroquois related homeobox 1
, Iroquois homeobox protein 1-A
, homeobox Iro protein
, iroquois-class homeodomain protein irx-1-A
, LOW QUALITY PROTEIN: iroquois-class homeodomain protein IRX-1
, Iroquois homeobox protein 1-B
, iroquois-class homeodomain protein irx-1-B