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TUBA1A 产品

(Tubulin, alpha 1a (Tuba1a))
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].

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Featured TUBA1A Categories

TUBA1A 抗体

High quality antibodies with extensive validation data.

TUBA1A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

TUBA1A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TUBA1A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (7)
Cat. No. ABIN2856707
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF, IP, FACS
Validations
  • (6)
Cat. No. ABIN7127861
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF
Validations
  • (1)
  • (4)
Cat. No. ABIN521658
Quantity 100 μg
Datasheet Datasheet

Recommended TUBA1A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960236
Quantity 96 tests
Datasheet Datasheet
Reactivity Monkey
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6200875
Quantity 96 tests
Datasheet Datasheet

Recommended TUBA1A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125523
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324100
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324098
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our TUBA1A Products

Chiu, Wen, Wang, Hsu, Tsai, Hung, Tseng, Shyr: "Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 97, (2018) (PubMed).

Ambadipudi, Georges: "Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1001-1006, (2017) (PubMed).

Schmid, Sailland, Novak, Baumlin, Fregien, Salathe: "Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways." in: FEBS letters, Vol. 591, Issue 21, pp. 3493-3506, (2017) (PubMed).

Niemeyer, Kang, Shin, Furlan, Erlacher, Bunin, Bunda, Finklestein, Sakamoto, Gorr, Mehta, Schmid, Kropshofer, Corbacioglu, Lang, Klein, Schlegel, Heinzmann, Schneider, Starý, van den Heuvel-Eibrink et al.: "Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia. ..." in: Nature genetics, Vol. 42, Issue 9, pp. 794-800, (2010) (PubMed).

Fourest-Lieuvin, Peris, Gache, Garcia-Saez, Juillan-Binard, Lantez, Job: "Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1." in: Molecular biology of the cell, Vol. 17, Issue 3, pp. 1041-50, (2006) (PubMed).

Westermann, Weber: "Post-translational modifications regulate microtubule function." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 12, pp. 938-47, (2003) (PubMed).

Synonyms and alternative names related to TUBA1A

tubulin, alpha 1A (Tuba1a), tubulin alpha 1a (TUBA1A), tubulin, alpha 1a (TUBA1A), tubulin alpha-1B chain (LOC608147), tubulin alpha-1A chain (LOC100392817), tubulin alpha-3 chain-like (LOC425049), tubulin, alpha 1a (tuba1a), alpha-Tubulin at 84B (alphaTub84B), tubulin alpha-1A chain (LOC100051840), tubulin alpha-1A chain (LOC100340483), tubulin alpha-1A chain (LOC100726777), tubulin alpha 1a L homeolog (tuba1a.L), 1t, a-tub84B, a1t, alpha-Tub, alpha-tub, alpha-Tub84B, alpha-tub84B, alpha-tubulin, Alpha-Tubulin84B, alpha-tubulin 84B, alpha1, alpha1t, alpha1tub, alpha1tub84B, alpha84B, ALPHA 84C, alphaT, alphat-1, alphaTUB, alphaTub, alphatub, alphaTub1, alphaTub84, alphatub84, alphaTUB84B, alphatub84B, anon-EST:Liang-1.59, anon-EST:Liang-2.30, aTub84B, B-ALPHA-1, b-alpha-1, BEST:LD32507, CG1913, chr3R:2914276..2914416, clone 1.59, clone 2.30, DM1alpha, Dmel\CG1913, DTA1, l(3)84Bd, l(3)g3, LIS3, lis3, ms(3)nc33, nc33, T, Talpha1, TBA1_DROME, Tub, tub, Tub1C, Tub 84B, Tuba-1, Tuba1, TUBA1A, Tuba1a, tuba1a, tuba1a-a, tuba1a-b, Tuba2, TUBA3, tuba3, TUBA3D, TUBA3E, Tuba84B, tubA84B, Tubalpha1, tubalpha1, tubulin, wu:fb37a10

Protein level used designations for TUBA1A

  • alpha-tubulin 1
  • tubulin alpha-1 chain
  • tubulin alpha-1A chain
  • tubulin, alpha 1
  • hum-a-tub1
  • hum-a-tub2
  • tubulin B-alpha-1
  • tubulin alpha-3 chain
  • tubulin, alpha, brain-specific
  • alpha-tubulin 3
  • tubulin, alpha 3
  • Talpha1 alpha-tubulin
  • alpha-tubulin isotype M-alpha-1
  • alpha-tubulin ubiquitous
  • tubulin K-alpha-1
  • tubulin alpha-1B chain
  • tubulin alpha-ubiquitous chain
  • tubulin, alpha 1a
  • tubulin alpha-1A chain-like
  • tubulin, alpha 3d
  • tubulin, alpha 3e
  • CG1913 gene product from transcript CG1913-RA
  • CG1913-PA
  • Tubulin-alpha1
  • alpha tubulin
  • alpha tubulin 84B
  • alpha-Tubulin
  • alpha-Tubulin 84B
  • alpha-tubulin84B
  • alpha1 tubulin
  • alpha1-tubulin
  • alphaT
  • alphaTub84B-PA
  • alphaTubulin 84B
  • alphaTubulin84B
  • alpha[[1]] tubulin
  • alpha[[1]]-tubulin
  • alphatubulin
  • tubulin
  • tubulin 1 alpha-chain
  • tubulin 1alpha
  • tubulin alpha1
  • tubulin alpha1 promoter
  • tubulin(alpha1)
  • tubulin1alpha
  • tubulin84B
  • Alpha-tubulin 1
  • Tubulin alpha-1 chain
  • tubulin alpha 3
  • Alpha-tubulin 2
  • Alpha-tubulin II
  • Tubulin alpha-2 chain
  • alpha-tubulin II
  • tubulin alpha 1a L homeolog
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