TUBA1A 产品
(Tubulin, alpha 1a (Tuba1a))
Categories
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].
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Featured TUBA1A Categories
TUBA1A 抗体
High quality antibodies with extensive validation data.
TUBA1A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
TUBA1A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TUBA1A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (1)
- (7)
Cat. No.
ABIN2856707
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF, IP, FACS
Validations
- (6)
Cat. No.
ABIN7127861
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (1)
- (4)
Cat. No.
ABIN521658
Quantity
100 μg
Datasheet
Datasheet
Recommended TUBA1A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960236
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Monkey
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6200875
Quantity
96 tests
Datasheet
Datasheet
Recommended TUBA1A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7544232
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7556658
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125523
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our TUBA1A Products
: "Fasudil inhibits proliferation and migration of Hep-2 laryngeal carcinoma cells." in: Drug design, development and therapy, Vol. 12, pp. 373-381, (2018) (PubMed).: "Attenuation of TGFBR2 expression and tumour progression in prostate cancer involve diverse hypoxia-regulated pathways." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 89, (2018) (PubMed).
: "Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 97, (2018) (PubMed).
: "Novel chemiluminescent Western blot blocking and antibody incubation solution for enhanced antibody-antigen interaction and increased specificity." in: Electrophoresis, Vol. 38, Issue 20, pp. 2631-2637, (2017) (PubMed).
: "Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1001-1006, (2017) (PubMed).
: "Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways." in: FEBS letters, Vol. 591, Issue 21, pp. 3493-3506, (2017) (PubMed).
: "Development of trastuzumab-resistant human gastric carcinoma cell lines and mechanisms of drug resistance." in: Scientific reports, Vol. 5, pp. 11634, (2015) (PubMed).
: "Glucose transporter-1 expression in CD133+ laryngeal carcinoma Hep-2 cells." in: Molecular medicine reports, Vol. 8, Issue 6, pp. 1695-700, (2013) (PubMed).
: "Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia. ..." in: Nature genetics, Vol. 42, Issue 9, pp. 794-800, (2010) (PubMed).
: "Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1." in: Molecular biology of the cell, Vol. 17, Issue 3, pp. 1041-50, (2006) (PubMed).
Synonyms and alternative names related to TUBA1A
tubulin, alpha 1A (Tuba1a), tubulin alpha 1a (TUBA1A), tubulin, alpha 1a (TUBA1A), tubulin alpha-1B chain (LOC608147), tubulin alpha-1A chain (LOC100392817), tubulin alpha-3 chain-like (LOC425049), tubulin, alpha 1a (tuba1a), alpha-Tubulin at 84B (alphaTub84B), tubulin alpha-1A chain (LOC100051840), tubulin alpha-1A chain (LOC100340483), tubulin alpha-1A chain (LOC100726777), tubulin alpha 1a L homeolog (tuba1a.L), 1t, a-tub84B, a1t, alpha-Tub, alpha-tub, alpha-Tub84B, alpha-tub84B, alpha-tubulin, Alpha-Tubulin84B, alpha-tubulin 84B, alpha1, alpha1t, alpha1tub, alpha1tub84B, alpha84B, ALPHA 84C, alphaT, alphat-1, alphaTUB, alphaTub, alphatub, alphaTub1, alphaTub84, alphatub84, alphaTUB84B, alphatub84B, anon-EST:Liang-1.59, anon-EST:Liang-2.30, aTub84B, B-ALPHA-1, b-alpha-1, BEST:LD32507, CG1913, chr3R:2914276..2914416, clone 1.59, clone 2.30, DM1alpha, Dmel\CG1913, DTA1, l(3)84Bd, l(3)g3, LIS3, lis3, ms(3)nc33, nc33, T, Talpha1, TBA1_DROME, Tub, tub, Tub1C, Tub 84B, Tuba-1, Tuba1, TUBA1A, Tuba1a, tuba1a, tuba1a-a, tuba1a-b, Tuba2, TUBA3, tuba3, TUBA3D, TUBA3E, Tuba84B, tubA84B, Tubalpha1, tubalpha1, tubulin, wu:fb37a10Protein level used designations for TUBA1A
- alpha-tubulin 1
- tubulin alpha-1 chain
- tubulin alpha-1A chain
- tubulin, alpha 1
- hum-a-tub1
- hum-a-tub2
- tubulin B-alpha-1
- tubulin alpha-3 chain
- tubulin, alpha, brain-specific
- alpha-tubulin 3
- tubulin, alpha 3
- Talpha1 alpha-tubulin
- alpha-tubulin isotype M-alpha-1
- alpha-tubulin ubiquitous
- tubulin K-alpha-1
- tubulin alpha-1B chain
- tubulin alpha-ubiquitous chain
- tubulin, alpha 1a
- tubulin alpha-1A chain-like
- tubulin, alpha 3d
- tubulin, alpha 3e
- CG1913 gene product from transcript CG1913-RA
- CG1913-PA
- Tubulin-alpha1
- alpha tubulin
- alpha tubulin 84B
- alpha-Tubulin
- alpha-Tubulin 84B
- alpha-tubulin84B
- alpha1 tubulin
- alpha1-tubulin
- alphaT
- alphaTub84B-PA
- alphaTubulin 84B
- alphaTubulin84B
- alpha[[1]] tubulin
- alpha[[1]]-tubulin
- alphatubulin
- tubulin
- tubulin 1 alpha-chain
- tubulin 1alpha
- tubulin alpha1
- tubulin alpha1 promoter
- tubulin(alpha1)
- tubulin1alpha
- tubulin84B
- Alpha-tubulin 1
- Tubulin alpha-1 chain
- tubulin alpha 3
- Alpha-tubulin 2
- Alpha-tubulin II
- Tubulin alpha-2 chain
- alpha-tubulin II
- tubulin alpha 1a L homeolog
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