This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008].
Bradshaw, Bader, Prikulis, Lueking, Müllner, Korth: "Aggregation of the protein TRIOBP-1 and its potential relevance to schizophrenia." in: PLoS ONE, Vol. 9, Issue 10, pp. e111196, (2014) (PubMed).
Aliases for TRIOBP 抗体
TRIO and F-actin binding protein (TRIOBP) 抗体 TRIO and F-actin-binding protein (LOC100354753) 抗体 TRIO and F-actin binding protein L homeolog (triobp.L) 抗体 TRIO and F-actin binding protein-like (TRIOBPL) 抗体 TRIO and F-actin binding protein (Triobp) 抗体 AI428493 抗体 DFNB28 抗体 dJ37E16.4 抗体 EST478828 抗体 mKIAA1662 抗体 tara 抗体 TARA 抗体 Tara 抗体