TRIM72 蛋白
(Tripartite Motif Containing 72 (TRIM72))
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).
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custom-made
TRIM72
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
TRIM72
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for TRIM72 蛋白
tripartite motif containing 72 (TRIM72) 蛋白tripartite motif containing 72, E3 ubiquitin protein ligase L homeolog (trim72.L) 蛋白
tripartite motif-containing 72 (Trim72) 蛋白
tripartite motif containing 72 (Trim72) 蛋白
BC067209 蛋白
MG53 蛋白
Mg53 蛋白
RGD1562778 蛋白
Trim72 蛋白
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