TRIM72 抗体
(Tripartite Motif Containing 72 (TRIM72))
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).
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Latest Publications for our TRIM72 抗体
: "Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor." in: Cardiovascular research, Vol. 110, Issue 2, pp. 178-87, (2016) (PubMed).: "The intracellular Ca²⁺ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy." in: Nature medicine, Vol. 20, Issue 10, pp. 1187-92, (2014) (PubMed).
: "Crystal structure of PRY-SPRY domain of human TRIM72." in: Proteins, Vol. 78, Issue 3, pp. 790-5, (2010) (PubMed).
: "The sequence and analysis of duplication-rich human chromosome 16. ..." in: Nature, Vol. 432, Issue 7020, pp. 988-94, (2004) (PubMed).
Aliases for TRIM72 抗体
tripartite motif containing 72 (TRIM72) 抗体tripartite motif containing 72, E3 ubiquitin protein ligase L homeolog (trim72.L) 抗体
tripartite motif-containing 72 (Trim72) 抗体
tripartite motif containing 72 (Trim72) 抗体
BC067209 抗体
MG53 抗体
Mg53 抗体
RGD1562778 抗体
Trim72 抗体
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