TRF2 抗体
(Telomeric Repeat Binding Factor 2 (TERF2))
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008].
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Rockland Original
TERF2
适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, Pig, 非洲爪蟾, Bat
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our TRF2 抗体
: "TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." in: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).: "Elevated TRF2 in advanced breast cancers with short telomeres." in: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).
: "The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine." in: Molecular pharmacology, Vol. 73, Issue 3, pp. 824-32, (2008) (PubMed).
: "Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation." in: Experimental cell research, Vol. 314, Issue 5, pp. 1115-24, (2008) (PubMed).
: "Telomere protection by mammalian Pot1 requires interaction with Tpp1." in: Nature structural & molecular biology, Vol. 14, Issue 8, pp. 754-61, (2007) (PubMed).
: "Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase." in: Current biology : CB, Vol. 16, Issue 13, pp. 1295-302, (2006) (PubMed).
: "TRF2 inhibition triggers apoptosis and reduces tumourigenicity of human melanoma cells." in: European journal of cancer (Oxford, England : 1990), Vol. 42, Issue 12, pp. 1881-8, (2006) (PubMed).
: "Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells." in: Journal of cell science, Vol. 119, Issue Pt 20, pp. 4247-56, (2006) (PubMed).
: "FLASH is required for histone transcription and S-phase progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 40, pp. 14808-12, (2006) (PubMed).
: "MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres." in: Genes & development, Vol. 20, Issue 23, pp. 3238-43, (2006) (PubMed).
Aliases for TRF2 抗体
telomeric repeat binding factor 2 (TERF2) 抗体telomeric repeat binding factor 2 (Terf2) 抗体
telomeric repeat binding factor 2 L homeolog (terf2.L) 抗体
TERF2 抗体
TRBF2 抗体
TRF2 抗体
trf2 抗体
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