(Trafficking Protein Particle Complex 6A (TRAPPC6A))
This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein may be involved in melanosome biogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012].
Williams, Cavus, Loccoh, Adelman, Daugherty, Smith, Canan, Janssen, Koenig, Kline, Mohler, Bradley: "Defining the molecular signatures of human right heart failure." in: Life sciences, Vol. 196, pp. 118-126, (2018) (PubMed).