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Transglutaminase 2 产品

(Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

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Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured Transglutaminase 2 Categories

Transglutaminase 2 抗体

High quality antibodies with extensive validation data.

Transglutaminase 2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Transglutaminase 2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Transglutaminase 2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (6)
Cat. No. ABIN520891
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (9)
Cat. No. ABIN7434158
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rabbit, Rat
Application IHC, IF, FACS, StM
Validations
  • (5)
Cat. No. ABIN6940725
Quantity 100 μg
Datasheet Datasheet

Recommended Transglutaminase 2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (6)
Cat. No. ABIN6574289
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960115
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6999448
Quantity 96 tests
Datasheet Datasheet

Recommended Transglutaminase 2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN7275723
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN7275724
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1322636
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Transglutaminase 2 Products

Wang, Lin, Han, Lu, Li, Hu, Feng, Chen, He: "Metformin attenuates TGF-β1-induced pulmonary fibrosis through inhibition of transglutaminase 2 and subsequent TGF-β pathways." in: 3 Biotech, Vol. 10, Issue 6, pp. 287, (2020) (PubMed).

Maffei, Laverrière, Wu, Triboulet, Perrinet, Duchateau, Matondo, Hollis, Gourley, Rupp, Keillor, Subtil: "Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells." in: The EMBO journal, Vol. 39, Issue 8, pp. e102166, (2020) (PubMed).

Guise, Engel, Williams, Mahdi, Bidwell, Chade: "Biopolymer-delivered vascular endothelial growth factor improves renal outcomes following revascularization." in: American journal of physiology. Renal physiology, Vol. 316, Issue 5, pp. F1016-F1025, (2019) (PubMed).

Philp, Siebeke, Clements, Miller, Habgood, John, Navaratnam, Hubbard, Jenkins, Johnson: "Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysis in Lung Fibrosis." in: American journal of respiratory cell and molecular biology, Vol. 58, Issue 5, pp. 594-603, (2018) (PubMed).

Becerik, Celec, Gürkan, Öztürk, Kamodyova, Atilla, Emingil: "Gingival Crevicular Fluid and Plasma Levels of Transglutaminase-2 and Oxidative Stress Markers in Cyclosporin A-Induced Gingival Overgrowth." in: Journal of periodontology, Vol. 87, Issue 12, pp. 1508-1516, (2018) (PubMed).

Markel, Noore, Emery, Bobnar, Kleinerman, Lindsey: "Using the Spleen as an In Vivo Systemic Immune Barometer Alongside Osteosarcoma Disease Progression and Immunotherapy with α-PD-L1." in: Sarcoma, Vol. 2018, pp. 8694397, (2018) (PubMed).

Chao, Huang, Yang, Sun: "Tissue transglutaminase is involved in mechanical load-induced osteogenic differentiation of human ligamentum flavum cells." in: Connective tissue research, Vol. 57, Issue 4, pp. 307-18, (2016) (PubMed).

Faria, Henriques, Matos, Daha, Pestana, Seelen: "Combined C4d and CD3 immunostaining predicts immunoglobulin (Ig)A nephropathy progression." in: Clinical and experimental immunology, Vol. 179, Issue 2, pp. 354-61, (2015) (PubMed).

Kanchan, Fuxreiter, Fésüs: "Physiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2." in: Cellular and molecular life sciences : CMLS, Vol. 72, Issue 16, pp. 3009-35, (2015) (PubMed).

Velez V, Romano, McKown, Green, Zhang, Raab, Ryan, Hutnik, Frierson, Laurie: "Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity." in: Investigative ophthalmology & visual science, Vol. 54, Issue 3, pp. 2123-32, (2013) (PubMed).

Synonyms and alternative names related to Transglutaminase 2

transglutaminase 2 (TGM2), transglutaminase 2, C polypeptide A (tgm2a), transglutaminase 2 (Tgm2), transglutaminase 2b (tgm2b), transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transglutaminase 2, C polypeptide (Tgm2), fc12b04, G-ALPHA-h, GNAH, G[a]h, TG2, TGase2, TgaseII, TGC, TGL2, tgm2, TGM2, tTG, tTGas, wu:fc12b04, zgc:101081, zgc:136700

Protein level used designations for Transglutaminase 2

  • C polypeptide, protein-glutamine-gamma-glutamyltransferase
  • TG(C)
  • TGase C
  • TGase H
  • TGase-2
  • TGase-H
  • protein-glutamine gamma-glutamyltransferase 2
  • protein-glutamine-gamma-glutamyltransferase
  • tissue transglutaminase
  • transglutaminase C
  • transglutaminase H
  • transglutaminase-2
  • TG2c
  • transglutaminase 2
  • tissue-type transglutaminase
  • transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • TGC
  • C polypeptide
  • TG C
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