The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008].
custom-made
TRADD
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
TRADD
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
TNFRSF1A associated via death domain (TRADD) 蛋白 conjugal transfer protein D (traDd) 蛋白 TNFRSF1A-associated via death domain (Tradd) 蛋白 TNFRSF1A-associated via death domain L homeolog (tradd.L) 蛋白 tnfrsf1a-associated via death domain (tradd) 蛋白 TNFRSF1A associated via death domain (tradd) 蛋白 9130005N23Rik 蛋白 AA930854 蛋白 Hs.89862 蛋白 TRADD 蛋白 tradd 蛋白 wu:fc59e02 蛋白 zgc:103556 蛋白