TPMT 蛋白
(Thiopurine S-Methyltransferase (TPMT))
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008].
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21 results
Aliases for TPMT 蛋白
thiopurine S-methyltransferase L homeolog (tpmt.L) 蛋白thiopurine S-methyltransferase, tandem duplicate 2 (tpmt.2) 蛋白
thiopurine S-methyltransferase TpmT (tpmT) 蛋白
thiopurine S-methyltransferase (MCA0794) 蛋白
thiopurine S-methyltransferase (Pnap_4948) 蛋白
thiopurine S-methyltransferase (Hhal_1383) 蛋白
thiopurine S-methyltransferase (TK90_1044) 蛋白
thiopurine S-methyltransferase (Slit_1144) 蛋白
thiopurine S-methyltransferase (Tint_0842) 蛋白
Thiopurine S-methyltransferase (Fbal_3334) 蛋白
thiopurine S-methyltransferase (Celly_3188) 蛋白
thiopurine S-methyltransferase (Weevi_1737) 蛋白
Thiopurine S-methyltransferase (Psefu_2696) 蛋白
Thiopurine S-methyltransferase (Metme_3860) 蛋白
thiopurine methyltransferase (Tpmt) 蛋白
thiopurine S-methyltransferase (TPMT) 蛋白
thiopurine S-methyltransferase (Tpmt) 蛋白
AW106912 蛋白
MGC84277 蛋白
NHLRC1 蛋白
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