TNR1A Protein (AA 31-210) (GST tag)
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Quick Overview for TNR1A Protein (AA 31-210) (GST tag) (ABIN5712514)
抗原
蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 31-210
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标记
- This TNR1A protein is labelled with GST tag.
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序列
- VPHLGDREKR DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD CRECESGSFT ASENHLRHCL SCSKCRKEMG QVEISSCTVD RDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE NVKGTEDSGT
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纯化方法
- SDS-PAGE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1-2 mg/mL
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缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
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储存条件
- -80 °C,4 °C,-20 °C
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储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- TNR1A (Tumor Necrosis Factor Receptor Superfamily Member 1A (TNR1A))
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别名
- TNR1A
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背景
- Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
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分子量
- 47.6 kDa
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UniProt
- P19438
抗原
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