(Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011].
Wu, Huang, Hsieh, Hsiao, Lee, Lin: "EGFR-driven up-regulation of decoy receptor 3 in keratinocytes contributes to the pathogenesis of psoriasis." in: Biochimica et biophysica acta, Vol. 1832, Issue 10, pp. 1538-48, (2013) (PubMed).
Aliases for TNFRSF6B 抗体
TNF receptor superfamily member 6b (TNFRSF6B) 抗体 tumor necrosis factor receptor superfamily, member 11b (tnfrsf11b) 抗体 regulator of telomere elongation helicase 1 (RTEL1) 抗体 TNF receptor superfamily member 6b (tnfrsf6b) 抗体 TNF receptor superfamily member 6b L homeolog (tnfrsf6b.L) 抗体 DCR3 抗体 dcr3 抗体 DJ583P15.1.1 抗体 M68 抗体 m68 抗体 M68E 抗体 TR6 抗体 tr6 抗体