TLR9 抗体
(Toll-Like Receptor 9 (TLR9))
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008].
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Latest Publications for our TLR9 抗体
: "Differential expression patterns of Toll Like Receptors and Interleukin-37 between calcific aortic and mitral valve cusps in humans." in: Cytokine, Vol. 116, pp. 150-160, (2019) (PubMed).: "Co-expression of TLR-9 and MMP-13 is associated with the degree of tumour differentiation in prostate cancer." in: International journal of experimental pathology, Vol. 100, Issue 2, pp. 123-132, (2019) (PubMed).
: "A proliferation-inducing ligand (APRIL) induced hyper-production of IgA from tonsillar mononuclear cells in patients with IgA nephropathy." in: Cellular immunology, Vol. 341, pp. 103925, (2019) (PubMed).
: "Necroptosis in pulmonary macrophages mediates lipopolysaccharide-induced lung inflammatory injury by activating ZBP-1." in: International immunopharmacology, Vol. 77, pp. 105944, (2019) (PubMed).
: "Genistein modulates the expression of Toll-like receptors in experimental autoimmune encephalomyelitis." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 67, Issue 7, pp. 597-608, (2018) (PubMed).
: "Elevated intragraft expression of innate immunity and cell death-related markers is a risk factor for adverse graft outcome." in: Transplant immunology, Vol. 48, pp. 39-46, (2018) (PubMed).
: "High Tidal Volume Induces Mitochondria Damage and Releases Mitochondrial DNA to Aggravate the Ventilator-Induced Lung Injury." in: Frontiers in immunology, Vol. 9, pp. 1477, (2018) (PubMed).
: "Toll-like receptors 2, 4 and 9 and hypoxia markers HIF-1alpha and CAIX in pancreatic intraepithelial neoplasia." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 126, Issue 11, pp. 852-863, (2018) (PubMed).
: "Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients." in: Mediators of inflammation, Vol. 2017, pp. 2608349, (2017) (PubMed).
: "High toll-like receptor (TLR) 9 expression is associated with better prognosis in surgically treated pancreatic cancer patients." in: Virchows Archiv : an international journal of pathology, Vol. 470, Issue 4, pp. 401-410, (2017) (PubMed).
Aliases for TLR9 抗体
toll like receptor 9 (TLR9) 抗体toll-like receptor 9 (Tlr9) 抗体
CD289 抗体
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